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Long-term proteasomal inhibition in transgenic mice by UBB(+1) expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients.
Irmler M, Gentier RJ, Dennissen FJ, Schulz H, Bolle I, Hölter SM, Kallnik M, Cheng JJ, Klingenspor M, Rozman J, Ehrhardt N, Hermes DJ, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Meyer HE, Hopkins DA, Van Leeuwen FW, Beckers J. Irmler M, et al. Among authors: van leeuwen fw. Acta Neuropathol. 2012 Aug;124(2):187-97. doi: 10.1007/s00401-012-1003-7. Epub 2012 Jun 23. Acta Neuropathol. 2012. PMID: 22730000 Free PMC article.
Erratum: gene-environment interaction research and transgenic mouse models of Alzheimer's disease.
Chouliaras L, Sierksma AS, Kenis G, Prickaerts J, Lemmens MA, Brasnjevic I, van Donkelaar EL, Martinez-Martinez P, Losen M, De Baets MH, Kholod N, van Leeuwen FW, Hof PR, van Os J, Steinbusch HW, van den Hove DL, Rutten BP. Chouliaras L, et al. Among authors: van os j, van den hove dl, van donkelaar el, van leeuwen fw. Int J Alzheimers Dis. 2011 Jan 10;2010:356862. doi: 10.4061/2010/356862. Int J Alzheimers Dis. 2011. PMID: 21318175 Free PMC article. No abstract available.
Long-term proteasome dysfunction in the mouse brain by expression of aberrant ubiquitin.
Fischer DF, van Dijk R, van Tijn P, Hobo B, Verhage MC, van der Schors RC, Li KW, van Minnen J, Hol EM, van Leeuwen FW. Fischer DF, et al. Among authors: van der schors rc, van tijn p, van dijk r, van minnen j, van leeuwen fw. Neurobiol Aging. 2009 Jun;30(6):847-63. doi: 10.1016/j.neurobiolaging.2008.06.009. Epub 2008 Aug 28. Neurobiol Aging. 2009. PMID: 18760506
Paradoxical effects of mutant ubiquitin on Aβ plaque formation in an Alzheimer mouse model.
Verheijen BM, Stevens JAA, Gentier RJG, van 't Hekke CD, van den Hove DLA, Hermes DJHP, Steinbusch HWM, Ruijter JM, Grimm MOW, Haupenthal VJ, Annaert W, Hartmann T, van Leeuwen FW. Verheijen BM, et al. Among authors: van t hekke cd, van den hove dla, van leeuwen fw. Neurobiol Aging. 2018 Dec;72:62-71. doi: 10.1016/j.neurobiolaging.2018.08.011. Epub 2018 Aug 18. Neurobiol Aging. 2018. PMID: 30216939 Free article.
415 results