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A benign cultured colon adenoma bears three genetically altered colon cancer oncogenes, but progresses to tumorigenicity and transforming growth factor-beta independence without inactivating the p53 tumor suppressor gene.
Markowitz SD, Myeroff L, Cooper MJ, Traicoff J, Kochera M, Lutterbaugh J, Swiriduk M, Willson JK. Markowitz SD, et al. Among authors: lutterbaugh j. J Clin Invest. 1994 Mar;93(3):1005-13. doi: 10.1172/JCI117048. J Clin Invest. 1994. PMID: 8132740 Free PMC article.
Increased transversions in a novel mutator colon cancer cell line.
Eshleman JR, Donover PS, Littman SJ, Swinler SE, Li GM, Lutterbaugh JD, Willson JK, Modrich P, Sedwick WD, Markowitz SD, Veigl ML. Eshleman JR, et al. Among authors: lutterbaugh jd. Oncogene. 1998 Mar 5;16(9):1125-30. doi: 10.1038/sj.onc.1201629. Oncogene. 1998. PMID: 9528854
36 results