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Page 1
Clinical practice and implications of biomarker testing in biliary tract cancer: An observational study.
Welland S, Zöller AK, Mavroeidi IA, Tomczak A, Müller C, Yawen D, Zhang D, Keil F, Pangerl M, Zhou T, Taghizadeh H, Lange S, Kinzler MN, Shmanko K, Barsch M, Zimpel C, Djanani A, Schulze-Bergkamen H, Keyl J, Lüke F, Wirth T, Dill M, Longerich T, Petschnak S, Marquardt JU, Quante M, Weinmann A, Walter D, Pfarr N, Prager G, Doleschal B, Gonzalez-Carmona MA, Günther R, Scheiter A, Böck S, Bartels S, Gruenberger T, Venerito M, Springfeld C, Kasper S, Saborowski A, Vogel A. Welland S, et al. Among authors: springfeld c. JHEP Rep. 2025 Nov 4;8(1):101635. doi: 10.1016/j.jhepr.2025.101635. eCollection 2026 Jan. JHEP Rep. 2025. PMID: 41674898 Free PMC article.
TROPHIT1-a randomized, open-label, multicenter, phase II/III trial of sacituzumab govitecan compared to standard of care in metastatic colorectal cancer patients.
Köhler BC, Haag GM, Le Cornet L, Hoffmeister-Wittmann P, Schmidt M, Manjunath A, Vaquero-Siguero N, Jenzer M, Gimmel M, Stahler A, Stein A, Reichert M, Kasper S, Bitzer M, Jäger D, Springfeld C, Weber TF, Fröhling S, Steindorf K, Trumpp A, Schlenk RF, Jackstadt R. Köhler BC, et al. Among authors: springfeld c. ESMO Gastrointest Oncol. 2025 Jan 17;7:100118. doi: 10.1016/j.esmogo.2024.100118. eCollection 2025 Mar. ESMO Gastrointest Oncol. 2025. PMID: 41646480 Free PMC article.
Repotrectinib in NTRK fusion-positive advanced solid tumors: a phase 1/2 trial.
Besse B, Lin JJ, Bazhenova L, Goto K, de Langen AJ, Kim DW, Wolf J, Springfeld C, Popat S, Lim DWT, Nagasaka M, Hong JY, Baik CS, Hervieu A, Moreno V, Yang N, Kollengode K, Yang H, Xu Y, Calvet CY, Yuan Y, Hammell AB, Drilon A, Solomon BJ. Besse B, et al. Among authors: springfeld c. Nat Med. 2026 Feb;32(2):682-689. doi: 10.1038/s41591-025-04079-7. Epub 2026 Feb 4. Nat Med. 2026. PMID: 41639379 Free PMC article. Clinical Trial.
NQO1 as a predictor of response to adjuvant GemCap treatment for pancreatic cancer.
Williams D, Patel C, Murray K, Oldfield L, Small B, Barrera LN, O'Sullivan R, Birch-Ford J, Evans A, Campbell F, Perez-Mancera PA, Halloran CM, Palmer D, Greenhalf W, Copple IM, Goldring C, Hackert T, Jackson R, Neoptolemos JP, Springfeld C, Büchler MW, Michalski CW, Ghaneh P, Costello E. Williams D, et al. Among authors: springfeld c. J Natl Cancer Inst. 2025 Dec 1:djaf345. doi: 10.1093/jnci/djaf345. Online ahead of print. J Natl Cancer Inst. 2025. PMID: 41324572
Delivering precision oncology in metastatic breast cancer: Clinical impact of comprehensive genomic profiling-The CATCH experience.
Hlevnjak M, Heublein S, Thewes V, Wagener L, Pixberg C, Fremd C, Michel L, Maurer C, Buschhorn L, Dikow N, Feng F, Fröhling S, Herold-Mende C, Hirsch S, Hong C, Hübschmann D, Jassowicz L, Kozyulina P, Pfütze K, Schlenk RF, Sinn HP, Smetanay K, Springfeld C, Stenzinger A, Wagner C, Wolf S, Trumpp A, Jäger D, Zivanovic O, Zapatka M, Schneeweiss A, Lichter P. Hlevnjak M, et al. Among authors: springfeld c. Int J Cancer. 2026 Mar 15;158(6):1675-1689. doi: 10.1002/ijc.70208. Epub 2025 Oct 31. Int J Cancer. 2026. PMID: 41170836 Free PMC article.
Protocol: Faecal microbiota transfer in liver cancer to overcome resistance to atezolizumab/bevacizumab - a multicentre, randomised, placebo-controlled, double-blind phase II trial (the FLORA trial).
Rauber C, Roberti MP, Vehreschild MJ, Tsakmaklis A, Springfeld C, Teufel A, Ettrich T, Jochheim L, Kandulski A, Missios P, Mohr R, Reichart A, Waldschmidt DT, Sauer LD, Sander A, Schirmacher P, Jäger D, Michl P, Dill MT. Rauber C, et al. Among authors: springfeld c. BMJ Open. 2025 Sep 9;15(9):e097802. doi: 10.1136/bmjopen-2024-097802. BMJ Open. 2025. PMID: 40930564 Free PMC article.
140 results