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Adopting Duplex Sequencing™ Technology for Genetic Toxicity Testing: A Proof-of-Concept Mutagenesis Experiment with N-Ethyl-N-Nitrosourea (ENU)-Exposed Rats.
Smith-Roe SL, Hobbs CA, Hull V, Auman JT, Recio L, Streicker MA, Rivas MV, Pratt GA, Lo FY, Higgins JE, Schmidt EK, Williams LN, Nachmanson D, Valentine CC 3rd, Salk JJ, Witt KL. Smith-Roe SL, et al. bioRxiv [Preprint]. 2023 May 9:2023.05.08.539833. doi: 10.1101/2023.05.08.539833. bioRxiv. 2023. Update in: Mutat Res Genet Toxicol Environ Mutagen. 2023 Oct;891:503669. doi: 10.1016/j.mrgentox.2023.503669. PMID: 37214853 Free PMC article. Updated. Preprint.
Error-corrected next generation sequencing - Promises and challenges for genotoxicity and cancer risk assessment.
Marchetti F, Cardoso R, Chen CL, Douglas GR, Elloway J, Escobar PA, Harper T Jr, Heflich RH, Kidd D, Lynch AM, Myers MB, Parsons BL, Salk JJ, Settivari RS, Smith-Roe SL, Witt KL, Yauk CL, Young R, Zhang S, Minocherhomji S. Marchetti F, et al. Mutat Res Rev Mutat Res. 2023 Jul-Dec;792:108466. doi: 10.1016/j.mrrev.2023.108466. Epub 2023 Aug 27. Mutat Res Rev Mutat Res. 2023. PMID: 37643677 Free article. Review.
Adopting duplex sequencing technology for genetic toxicity testing: A proof-of-concept mutagenesis experiment with N-ethyl-N-nitrosourea (ENU)-exposed rats.
Smith-Roe SL, Hobbs CA, Hull V, Todd Auman J, Recio L, Streicker MA, Rivas MV, Pratt GA, Lo FY, Higgins JE, Schmidt EK, Williams LN, Nachmanson D, Valentine Iii CC, Salk JJ, Witt KL. Smith-Roe SL, et al. Mutat Res Genet Toxicol Environ Mutagen. 2023 Oct;891:503669. doi: 10.1016/j.mrgentox.2023.503669. Epub 2023 Aug 3. Mutat Res Genet Toxicol Environ Mutagen. 2023. PMID: 37770135 Free PMC article.
Transferability, Reproducibility and Sensitivity of Mutation Quantification by Duplex Sequencing.
Zhang S, Parsons BL, Fitzgerald D, Ashford A, Auman JT, Chen T, Dodge A, Elhajouji A, Pfaller L, Harris S, Higgins J, Hobbs CA, Marchetti F, Meier MJ, Myers MB, Salk J, Sahroui R, Schuster D, Settivari R, Smith-Roe SL, Yauk CL, Yan J, Williams A, Chen CL. Zhang S, et al. Among authors: smith roe sl. Environ Mol Mutagen. 2025 Aug;66(6-7):311-326. doi: 10.1002/em.70020. Epub 2025 Jun 30. Environ Mol Mutagen. 2025. PMID: 40586373 Free PMC article.
A cross-sectional clinical study in women to investigate possible genotoxicity and hematological abnormalities related to the use of black cohosh botanical dietary supplements.
Smith-Roe SL, Garantziotis S, Church RL, Bemis JC, Torous DK, Shepard KG, Hobbs CA, Waidyanatha S, Mutlu E, Shockley KR, Kissling GE, McBride SJ, Xie G, Cristy T, Pierfelice J, Witt KL. Smith-Roe SL, et al. Environ Mol Mutagen. 2022 Dec;63(8-9):389-399. doi: 10.1002/em.22516. Epub 2022 Nov 28. Environ Mol Mutagen. 2022. PMID: 36323641 Free PMC article.
Quantitative evaluation of genotoxicity data for risk assessment and regulatory decision-making: Time for a paradigm shift.
Sachse B, Schmeisser S, van Benthem J, Corvi R, Dogliotti E, Ertych N, Frötschl R, Gündel U, Herrmann K, Johnson G, Kneuer C, König J, Martus HJ, Pfuhler S, Smith-Roe S, Stopper H, White P, Schwerdtle T, Hensel A, Tralau T. Sachse B, et al. Environ Int. 2026 Feb;208:110070. doi: 10.1016/j.envint.2026.110070. Epub 2026 Jan 16. Environ Int. 2026. PMID: 41579678 Free article.
85 results