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Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits.
Niwa M, Kamiya A, Murai R, Kubo K, Gruber AJ, Tomita K, Lu L, Tomisato S, Jaaro-Peled H, Seshadri S, Hiyama H, Huang B, Kohda K, Noda Y, O'Donnell P, Nakajima K, Sawa A, Nabeshima T. Niwa M, et al. Among authors: gruber aj. Neuron. 2010 Feb 25;65(4):480-9. doi: 10.1016/j.neuron.2010.01.019. Neuron. 2010. PMID: 20188653 Free PMC article.
Replication-associated mechanisms contribute to an increased CpG > TpG mutation burden in mismatch repair-deficient cancers.
Ward JC, Soriano I, Thorn S, Fernández-Tajes J, Sherwood K, Gül G, Scheffers J, Frangou A, Kinnersley B, Kafetzopoulos I, Sproul D, Galavotti S, Palles C, Gruber AJ, Church DN, Tomlinson I. Ward JC, et al. Among authors: gruber aj. Genome Med. 2025 Aug 25;17(1):95. doi: 10.1186/s13073-025-01525-6. Genome Med. 2025. PMID: 40855317 Free PMC article.
Genomic landscape of diffuse glioma revealed by whole genome sequencing.
Kinnersley B, Jung J, Cornish AJ, Chubb D, Laxton R, Frangou A, Gruber AJ, Sud A, Caravagna G, Sottoriva A, Wedge DC, Booth T, Al-Sarraj S, Lawrence SED, Albanese E, Anichini G, Baxter D, Boukas A, Chowdhury YA, D'Urso P, Corns R, Dapaah A, Edlmann E, Greenway F, Grundy P, Hill CS, Jenkinson MD, Trichinopoly Krishna S, Smith S, Manivannan S, Martin AJ, Matloob S, Mukherjee S, O'Neill K, Plaha P, Pollock J, Price S, Rominiyi O, Sachdev B, Saeed F, Sinha S, Thorne L, Ughratdar I, Whitfield P, Youshani AS, Bulbeck H, Arumugam P, Houlston R, Ashkan K. Kinnersley B, et al. Among authors: gruber aj. Nat Commun. 2025 May 7;16(1):4233. doi: 10.1038/s41467-025-59156-9. Nat Commun. 2025. PMID: 40335506 Free PMC article.
Causes of evolutionary divergence in prostate cancer.
Esentürk E, Sahli A, Haberland V, Ziuboniewicz A, Wirth C, Bova GS, Bristow RG, Brook MN, Brors B, Butler A, Cancel-Tassin G, Cheng KC, Cooper CS, Corcoran NM, Cussenot O, Eeles RA, Favero F, Gerhauser C, Gihawi A, Girma EG, Gnanapragasam VJ, Gruber AJ, Hamid A, Hayes VM, He HH, Hovens CM, Imada EL, Jakobsdottir GM, Jung CH, Khani F, Kote-Jarai Z, Lamy P, Leeman G, Loda M, Lutsik P, Marchionni L, Molania R, Papenfuss AT, Pellegrina D, Pope B, Queiroz LR, Rausch T, Reimand J, Robinson B, Schlomm T, Sørensen KD, Uhrig S, Weischenfeldt J, Xu Y, Yamaguchi TN, Zanettini C, Lynch AG, Wedge DC, Brewer DS, Woodcock DJ. Esentürk E, et al. Among authors: gruber aj. ArXiv [Preprint]. 2025 Mar 17:arXiv:2503.13189v1. ArXiv. 2025. PMID: 40166741 Free PMC article. Preprint.
The long way from raw data to NAM-based information: Overview on data layers and processing steps.
Blum J, Brüll M, Hengstler JG, Dietrich DR, Gruber AJ, Dipalo M, Kraushaar U, Mangas I, Terron A, Fritsche E, Marx-Stoelting P, Hardy B, Schepky A, Escher S, Hartung T, Landsiedel R, Odermatt A, Sachana M, Koch K, Dönmez A, Masjosthusmann S, Bothe K, Schildknecht S, Beilmann M, Beltman JB, Fitzpatrick S, Mangerich A, Rehm M, Tangianu S, Zickgraf FM, Kamp H, Burger G, van de Water B, Kleinstreuer N, White A, Leist M. Blum J, et al. Among authors: gruber aj. ALTEX. 2025;42(1):167-180. doi: 10.14573/altex.2412171. ALTEX. 2025. PMID: 39817434 Free article.
107 results