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ZC3H4, a novel regulator of mitochondrial complex I, impacts prostate stromal cell senescence, attachment, adhesion and anoikis resistance.
Liu TT, Carrarini MJ, Myklebust LK, Skalitzky KO, El-Khoury N, Sipula IJ, Chang A, Soman V, Liu A, Ihejirika N, Chandran UR, Jurczak MJ, Ricke WA, DeFranco DB, Pascal LE. Liu TT, et al. Among authors: pascal le. Cell Death Dis. 2025 Oct 21;16(1):741. doi: 10.1038/s41419-025-08027-8. Cell Death Dis. 2025. PMID: 41120279 Free PMC article.
Dietary methionine restriction started late in life promotes healthy aging in a sex-specific manner.
Hernández-Arciga U, Stamenkovic C, Yadav S, Nicoletti C, Albalawy WN, Al Hammood F, Gonzalez TF, Naikwadi MU, Graham A, Smarz C, Little GJ, Williams SG, McMahon B, Sipula IJ, Vandevender AM, Chuan B, Cooke D, Pinto AFM, Flores LC, Hartman HL, Diedrich JK, Brooke RT, Alder JK, Frahm KA, Pascal LE, Stolt E, Troensegaard H, Øvrebø B, Elshorbagy A, Molina E, Vinknes KJ, Tan RJ, Weisz OA, Bueno M, Eickelberg O, Steinhauser ML, Finkel T, Ables GP, Ikeno Y, Olsen T, Sacco A, Jurczak MJ, Sukoff Rizzo SJ, Parkhitko AA. Hernández-Arciga U, et al. Among authors: pascal le. Sci Adv. 2025 Apr 18;11(16):eads1532. doi: 10.1126/sciadv.ads1532. Epub 2025 Apr 16. Sci Adv. 2025. PMID: 40238871 Free PMC article.
Benign prostatic hyperplasia nodules in patients treated with celecoxib and/or finasteride have reduced levels of NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, a mitochondrial protein essential for efficient function of the electron transport chain.
Liu TT, Igarashi T, El-Khoury N, Ihejirika N, Paxton K, Jaumotte J, Dhir R, Hudson CN, Nelson JB, DeFranco DB, Yoshimura N, Wang Z, Pascal LE. Liu TT, et al. Among authors: pascal le. Prostate. 2024 Oct;84(14):1309-1319. doi: 10.1002/pros.24766. Epub 2024 Jul 14. Prostate. 2024. PMID: 39004950 Free PMC article.
78 results