Nebert DW - Search Results

1

Glutathione defense mechanism in liver injury: insights from animal models.

Chen Y, Dong H, Thompson DC, Shertzer HG, Nebert DW, Vasiliou V. Chen Y, et al. Among authors: nebert dw. Food Chem Toxicol. 2013 Oct;60:38-44. doi: 10.1016/j.fct.2013.07.008. Epub 2013 Jul 12. Food Chem Toxicol. 2013. PMID: 23856494 Free PMC article. Review.

2

Glutathione-deficient mice are susceptible to TCDD-Induced hepatocellular toxicity but resistant to steatosis.

Chen Y, Krishan M, Nebert DW, Shertzer HG. Chen Y, et al. Among authors: nebert dw. Chem Res Toxicol. 2012 Jan 13;25(1):94-100. doi: 10.1021/tx200242a. Epub 2011 Dec 6. Chem Res Toxicol. 2012. PMID: 22082335

3

Genetically altered mice to evaluate glutathione homeostasis in health and disease.

Dalton TP, Chen Y, Schneider SN, Nebert DW, Shertzer HG. Dalton TP, et al. Among authors: nebert dw. Free Radic Biol Med. 2004 Nov 15;37(10):1511-26. doi: 10.1016/j.freeradbiomed.2004.06.040. Free Radic Biol Med. 2004. PMID: 15477003 Review.

4

Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels.

Chen Y, Shertzer HG, Schneider SN, Nebert DW, Dalton TP. Chen Y, et al. Among authors: nebert dw. J Biol Chem. 2005 Oct 7;280(40):33766-74. doi: 10.1074/jbc.M504604200. Epub 2005 Aug 4. J Biol Chem. 2005. PMID: 16081425 Free article.

5

Interaction between the catalytic and modifier subunits of glutamate-cysteine ligase.

Yang Y, Chen Y, Johansson E, Schneider SN, Shertzer HG, Nebert DW, Dalton TP. Yang Y, et al. Among authors: nebert dw. Biochem Pharmacol. 2007 Jul 15;74(2):372-81. doi: 10.1016/j.bcp.2007.02.003. Epub 2007 Feb 12. Biochem Pharmacol. 2007. PMID: 17517378

6

Early onset senescence occurs when fibroblasts lack the glutamate-cysteine ligase modifier subunit.

Chen Y, Johansson E, Fan Y, Shertzer HG, Vasiliou V, Nebert DW, Dalton TP. Chen Y, et al. Among authors: nebert dw. Free Radic Biol Med. 2009 Aug 15;47(4):410-8. doi: 10.1016/j.freeradbiomed.2009.05.003. Epub 2009 May 8. Free Radic Biol Med. 2009. PMID: 19427898 Free PMC article.

7

Oral N-acetylcysteine rescues lethality of hepatocyte-specific Gclc-knockout mice, providing a model for hepatic cirrhosis.

Chen Y, Johansson E, Yang Y, Miller ML, Shen D, Orlicky DJ, Shertzer HG, Vasiliou V, Nebert DW, Dalton TP. Chen Y, et al. Among authors: nebert dw. J Hepatol. 2010 Dec;53(6):1085-94. doi: 10.1016/j.jhep.2010.05.028. Epub 2010 Aug 11. J Hepatol. 2010. PMID: 20810184 Free PMC article.

8

Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response.

Yang Y, Dieter MZ, Chen Y, Shertzer HG, Nebert DW, Dalton TP. Yang Y, et al. Among authors: nebert dw. J Biol Chem. 2002 Dec 20;277(51):49446-52. doi: 10.1074/jbc.M209372200. Epub 2002 Oct 15. J Biol Chem. 2002. PMID: 12384496 Free article.

9

Hepatocyte-specific Gclc deletion leads to rapid onset of steatosis with mitochondrial injury and liver failure.

Chen Y, Yang Y, Miller ML, Shen D, Shertzer HG, Stringer KF, Wang B, Schneider SN, Nebert DW, Dalton TP. Chen Y, et al. Among authors: nebert dw. Hepatology. 2007 May;45(5):1118-28. doi: 10.1002/hep.21635. Hepatology. 2007. PMID: 17464988

10

Update of human and mouse matrix metalloproteinase families.

Jackson BC, Nebert DW, Vasiliou V. Jackson BC, et al. Among authors: nebert dw. Hum Genomics. 2010 Feb;4(3):194-201. doi: 10.1186/1479-7364-4-3-194. Hum Genomics. 2010. PMID: 20368140 Free PMC article.

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