Modlich U - Search Results

1

Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML.

Chaturvedi A, Araujo Cruz MM, Jyotsana N, Sharma A, Yun H, Görlich K, Wichmann M, Schwarzer A, Preller M, Thol F, Meyer J, Haemmerle R, Struys EA, Jansen EE, Modlich U, Li Z, Sly LM, Geffers R, Lindner R, Manstein DJ, Lehmann U, Krauter J, Ganser A, Heuser M. Chaturvedi A, et al. Among authors: modlich u. Blood. 2013 Oct 17;122(16):2877-87. doi: 10.1182/blood-2013-03-491571. Epub 2013 Aug 16. Blood. 2013. PMID: 23954893 Free article.

2

Safety and efficacy in retrovirally modified haematopoietic cell therapy.

Li Z, Modlich U, Baum C. Li Z, et al. Among authors: modlich u. Best Pract Res Clin Haematol. 2004 Sep;17(3):493-503. doi: 10.1016/j.beha.2004.05.009. Best Pract Res Clin Haematol. 2004. PMID: 15498719 Review.

3

Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis.

Modlich U, Kustikova OS, Schmidt M, Rudolph C, Meyer J, Li Z, Kamino K, von Neuhoff N, Schlegelberger B, Kuehlcke K, Bunting KD, Schmidt S, Deichmann A, von Kalle C, Fehse B, Baum C. Modlich U, et al. Blood. 2005 Jun 1;105(11):4235-46. doi: 10.1182/blood-2004-11-4535. Epub 2005 Feb 15. Blood. 2005. PMID: 15713797 Free article.

4

Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors.

Baum C, Kustikova O, Modlich U, Li Z, Fehse B. Baum C, et al. Among authors: modlich u. Hum Gene Ther. 2006 Mar;17(3):253-63. doi: 10.1089/hum.2006.17.253. Hum Gene Ther. 2006. PMID: 16544975 Review.

5

Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity.

Modlich U, Bohne J, Schmidt M, von Kalle C, Knöss S, Schambach A, Baum C. Modlich U, et al. Blood. 2006 Oct 15;108(8):2545-53. doi: 10.1182/blood-2005-08-024976. Epub 2006 Jul 6. Blood. 2006. PMID: 16825499 Free PMC article.

6

Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways.

Kustikova OS, Geiger H, Li Z, Brugman MH, Chambers SM, Shaw CA, Pike-Overzet K, de Ridder D, Staal FJ, von Keudell G, Cornils K, Nattamai KJ, Modlich U, Wagemaker G, Goodell MA, Fehse B, Baum C. Kustikova OS, et al. Among authors: modlich u. Blood. 2007 Mar 1;109(5):1897-907. doi: 10.1182/blood-2006-08-044156. Epub 2006 Nov 21. Blood. 2007. PMID: 17119121 Free PMC article.

7

Physiological promoters reduce the genotoxic risk of integrating gene vectors.

Zychlinski D, Schambach A, Modlich U, Maetzig T, Meyer J, Grassman E, Mishra A, Baum C. Zychlinski D, et al. Among authors: modlich u. Mol Ther. 2008 Apr;16(4):718-25. doi: 10.1038/mt.2008.5. Epub 2008 Mar 4. Mol Ther. 2008. PMID: 18334985 Free article.

8

Murine hematopoietic stem cell transduction using retroviral vectors.

Modlich U, Schambach A, Li Z, Schiedlmeier B. Modlich U, et al. Methods Mol Biol. 2009;506:23-31. doi: 10.1007/978-1-59745-409-4_3. Methods Mol Biol. 2009. PMID: 19110617

9

Leukemia diagnosis in murine bone marrow transplantation models.

Li Z, Modlich U, Anjali M. Li Z, et al. Among authors: modlich u. Methods Mol Biol. 2009;506:311-29. doi: 10.1007/978-1-59745-409-4_21. Methods Mol Biol. 2009. PMID: 19110635

10

Gene therapy of MPL deficiency: challenging balance between leukemia and pancytopenia.

Wicke DC, Meyer J, Buesche G, Heckl D, Kreipe H, Li Z, Welte KH, Ballmaier M, Baum C, Modlich U. Wicke DC, et al. Among authors: modlich u. Mol Ther. 2010 Feb;18(2):343-52. doi: 10.1038/mt.2009.233. Epub 2009 Oct 20. Mol Ther. 2010. PMID: 19844195 Free PMC article.

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