Cuny GD - Search Results

1

Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants.

Mohedas AH, Wang Y, Sanvitale CE, Canning P, Choi S, Xing X, Bullock AN, Cuny GD, Yu PB. Mohedas AH, et al. Among authors: cuny gd. J Med Chem. 2014 Oct 9;57(19):7900-15. doi: 10.1021/jm501177w. Epub 2014 Sep 4. J Med Chem. 2014. PMID: 25101911 Free PMC article.

2

Discovery of inhibitors that elucidate the role of UCH-L1 activity in the H1299 lung cancer cell line.

Liu Y, Lashuel HA, Choi S, Xing X, Case A, Ni J, Yeh LA, Cuny GD, Stein RL, Lansbury PT Jr. Liu Y, et al. Among authors: cuny gd. Chem Biol. 2003 Sep;10(9):837-46. doi: 10.1016/j.chembiol.2003.08.010. Chem Biol. 2003. PMID: 14522054

3

Synthesis, receptor binding and functional studies of mesoridazine stereoisomers.

Choi S, Haggart D, Toll L, Cuny GD. Choi S, et al. Among authors: cuny gd. Bioorg Med Chem Lett. 2004 Sep 6;14(17):4379-82. doi: 10.1016/j.bmcl.2004.06.078. Bioorg Med Chem Lett. 2004. PMID: 15357957

4

Structure-activity relationship study of novel tissue transglutaminase inhibitors.

Duval E, Case A, Stein RL, Cuny GD. Duval E, et al. Among authors: cuny gd. Bioorg Med Chem Lett. 2005 Apr 1;15(7):1885-9. doi: 10.1016/j.bmcl.2005.02.005. Bioorg Med Chem Lett. 2005. PMID: 15780627

5

Defining Cdk5 ligand chemical space with small molecule inhibitors of tau phosphorylation.

Ahn JS, Radhakrishnan ML, Mapelli M, Choi S, Tidor B, Cuny GD, Musacchio A, Yeh LA, Kosik KS. Ahn JS, et al. Among authors: cuny gd. Chem Biol. 2005 Jul;12(7):811-23. doi: 10.1016/j.chembiol.2005.05.011. Chem Biol. 2005. PMID: 16039528

6

Structure-activity relationship study of novel necroptosis inhibitors.

Teng X, Degterev A, Jagtap P, Xing X, Choi S, Denu R, Yuan J, Cuny GD. Teng X, et al. Among authors: cuny gd. Bioorg Med Chem Lett. 2005 Nov 15;15(22):5039-44. doi: 10.1016/j.bmcl.2005.07.077. Bioorg Med Chem Lett. 2005. PMID: 16153840

7

Synthesis of hydantoins from enantiomerically pure alpha-amino amides without epimerization.

Zhang D, Xing X, Cuny GD. Zhang D, et al. Among authors: cuny gd. J Org Chem. 2006 Feb 17;71(4):1750-3. doi: 10.1021/jo052474s. J Org Chem. 2006. PMID: 16468841

8

Small molecules that enhance the catalytic efficiency of HLA-DM.

Nicholson MJ, Moradi B, Seth NP, Xing X, Cuny GD, Stein RL, Wucherpfennig KW. Nicholson MJ, et al. Among authors: cuny gd. J Immunol. 2006 Apr 1;176(7):4208-20. doi: 10.4049/jimmunol.176.7.4208. J Immunol. 2006. PMID: 16547258 Free PMC article.

9

Structure-activity relationship study of tricyclic necroptosis inhibitors.

Jagtap PG, Degterev A, Choi S, Keys H, Yuan J, Cuny GD. Jagtap PG, et al. Among authors: cuny gd. J Med Chem. 2007 Apr 19;50(8):1886-95. doi: 10.1021/jm061016o. Epub 2007 Mar 16. J Med Chem. 2007. PMID: 17361994

10

Structure-activity relationship, kinetic mechanism, and selectivity for a new class of ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitors.

Mermerian AH, Case A, Stein RL, Cuny GD. Mermerian AH, et al. Among authors: cuny gd. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3729-32. doi: 10.1016/j.bmcl.2007.04.027. Epub 2007 Apr 10. Bioorg Med Chem Lett. 2007. PMID: 17449248

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