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Metformin for patients with metastatic prostate cancer starting androgen deprivation therapy: a randomised phase 3 trial of the STAMPEDE platform protocol.
Gillessen S, Murphy L, James ND, Sachdeva A, El-Taji O, Abdel-Aty H, Adler AI, Amos C, Attard G, Varughese M, Gale J, Brown S, Srihari N, Birtle AJ, Brown M, Chan K, Chowdhury S, Cross W, Dearnaley DP, Din O, Dutey-Magni P, Gilbert DC, Gilson C, Gray S, Grist E, Hofmann U, Hudson AM, Jain Y, Jeyasangar G, Jones R, Kayani M, Langley RE, Malik Z, Mason MD, Matheson D, McAlpine C, Macnair A, Millman R, Murphy C, Padden-Modi M, Parikh O, Parker C, Rush H, Russell M, Srinivasan R, Sundar S, Tanguay JS, Turco F, Williams P, Sydes MR, Parmar MKB, Brown LC, Clarke NW; STAMPEDE investigators. Gillessen S, et al. Lancet Oncol. 2025 Aug;26(8):1018-1030. doi: 10.1016/S1470-2045(25)00231-1. Epub 2025 Jul 7. Lancet Oncol. 2025. PMID: 40639383 Free PMC article. Clinical Trial.
Common AAV gene therapy vectors show nonselective transduction of ex vivo human brain tissue.
McGinnis JP, Ortiz-Guzman J, Guevara MC, Mallannagari S, Belfort BDW, Bao S, Srivastava S, Morkas M, Ji E, Addison A, Tantry EK, Chen S, Wang Y, Chen Z, Katlowitz KA, Lange JJ, Blessing MM, Mohila CA, Ljungberg MC, Aldave G, Jalali A, Patel A, Sheth SA, Weiner HL, Gopinath S, Rao G, Harmanci AS, Curry DJ, Arenkiel BR. McGinnis JP, et al. Among authors: addison a. Mol Ther Methods Clin Dev. 2025 May 21;33(2):101494. doi: 10.1016/j.omtm.2025.101494. eCollection 2025 Jun 12. Mol Ther Methods Clin Dev. 2025. PMID: 40525125 Free PMC article.
Some thio-ether-ketones and their related derivatives.
O'Connor MA, Pavlishchuk AV, Butcher RJ, Pavlishchuk VV, Addison AW. O'Connor MA, et al. Among authors: addison aw. Acta Crystallogr E Crystallogr Commun. 2025 May 13;81(Pt 6):520-529. doi: 10.1107/S2056989025004037. eCollection 2025 Jun 1. Acta Crystallogr E Crystallogr Commun. 2025. PMID: 40487687 Free PMC article.
Plasma AR Alterations and Timing of Intensified Hormone Treatment for Prostate Cancer: the STAMPEDE Phase 3 Randomized Clinical Trial.
Leone G, Orlando F, Dutey-Magni P, Vainauskas O, Grist E, Ciani Y, Lall S, Thakali S, Wingate A, Wetterskog D, Sachdeva A, Sydes MR, McPhail N, Sreenivasan T, O'Sullivan JM, Clarke NW, Parmar MKB, Brown LC, James ND, Demichelis F, Attard G; STAMPEDE collaborators. Leone G, et al. JAMA Oncol. 2025 Feb 27;11(4):426-9. doi: 10.1001/jamaoncol.2024.7051. Online ahead of print. JAMA Oncol. 2025. PMID: 40014335
Cell type transcriptional identities are maintained in cultured ex vivo human brain tissue.
McGinnis JP, Ortiz-Guzman J, Mallannagari S, Guevara MC, Belfort BDW, Bao S, Srivastava S, Morkas M, Ji E, Katlowitz KA, Addison A, Tantry EK, Blessing MM, Mohila CA, Gadgil N, McClugage SG, Bauer DF, Whitehead WE, Aldave G, Tanweer O, Jaleel N, Jalali A, Patel AJ, Sheth SA, Weiner HL, Gopinath S, Rao G, Harmanci AS, Curry D, Arenkiel BR. McGinnis JP, et al. Among authors: addison a. bioRxiv [Preprint]. 2024 Dec 20:2024.12.19.629223. doi: 10.1101/2024.12.19.629223. bioRxiv. 2024. PMID: 39763930 Free PMC article. Preprint.
145 results