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Circulating giant macrophages as a potential biomarker of solid tumors.
Adams DL, Martin SS, Alpaugh RK, Charpentier M, Tsai S, Bergan RC, Ogden IM, Catalona W, Chumsri S, Tang CM, Cristofanilli M. Adams DL, et al. Among authors: martin ss. Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3514-9. doi: 10.1073/pnas.1320198111. Epub 2014 Feb 18. Proc Natl Acad Sci U S A. 2014. PMID: 24550495 Free PMC article.
The combinatorial activation of the PI3K and Ras/MAPK pathways is sufficient for aggressive tumor formation, while individual pathway activation supports cell persistence.
Thompson KN, Whipple RA, Yoon JR, Lipsky M, Charpentier MS, Boggs AE, Chakrabarti KR, Bhandary L, Hessler LK, Martin SS, Vitolo MI. Thompson KN, et al. Among authors: martin ss. Oncotarget. 2015 Nov 3;6(34):35231-46. doi: 10.18632/oncotarget.6159. Oncotarget. 2015. PMID: 26497685 Free PMC article.
773 results