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Integrative analysis of 111 reference human epigenomes.
Roadmap Epigenomics Consortium; Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, Sarkar A, Quon G, Sandstrom RS, Eaton ML, Wu YC, Pfenning AR, Wang X, Claussnitzer M, Liu Y, Coarfa C, Harris RA, Shoresh N, Epstein CB, Gjoneska E, Leung D, Xie W, Hawkins RD, Lister R, Hong C, Gascard P, Mungall AJ, Moore R, Chuah E, Tam A, Canfield TK, Hansen RS, Kaul R, Sabo PJ, Bansal MS, Carles A, Dixon JR, Farh KH, Feizi S, Karlic R, Kim AR, Kulkarni A, Li D, Lowdon R, Elliott G, Mercer TR, Neph SJ, Onuchic V, Polak P, Rajagopal N, Ray P, Sallari RC, Siebenthall KT, Sinnott-Armstrong NA, Stevens M, Thurman RE, Wu J, Zhang B, Zhou X, Beaudet AE, Boyer LA, De Jager PL, Farnham PJ, Fisher SJ, Haussler D, Jones SJ, Li W, Marra MA, McManus MT, Sunyaev S, Thomson JA, Tlsty TD, Tsai LH, Wang W, Waterland RA, Zhang MQ, Chadwick LH, Bernstein BE, Costello JF, Ecker JR, Hirst M, Meissner A, Milosavljevic A, Ren B, Stamatoyannopoulos JA, Wang T, Kellis M. Roadmap Epigenomics Consortium, et al. Among authors: waterland ra. Nature. 2015 Feb 19;518(7539):317-30. doi: 10.1038/nature14248. Nature. 2015. PMID: 25693563 Free PMC article.
Mouse metastable epialleles are extremely rare.
Gunasekara CJ, Maduranga U, Zhang T, Wells JN, Baker MS, Laritsky E, Li Y, Coarfa C, Zhu Y, Waterland RA. Gunasekara CJ, et al. Among authors: waterland ra. Nucleic Acids Res. 2025 Jul 19;53(14):gkaf624. doi: 10.1093/nar/gkaf624. Nucleic Acids Res. 2025. PMID: 40694849 Free PMC article.
Human genomic regions of systemic interindividual epigenetic variation are implicated in neurodevelopmental and metabolic disorders.
Chang WJ, Maduranga U, Gunasekara CJ, Yang A, Hirschtritt M, Rodriguez K, Coarfa C, Jun G, Hanis CL, Flanagan JM, Gorlov IP, Amos CI, Wiemels JL, Schaefer CA, Susser ES, Waterland RA. Chang WJ, et al. Among authors: waterland ra. medRxiv [Preprint]. 2025 Feb 12:2025.02.10.25322021. doi: 10.1101/2025.02.10.25322021. medRxiv. 2025. PMID: 39990551 Free PMC article. Preprint.
Systemic interindividual DNA methylation variants in cattle share major hallmarks with those in humans.
Chang WJ, Baker MS, Laritsky E, Gunasekara CJ, Maduranga U, Galliou JC, McFadden JW, Waltemyer JR, Berggren-Thomas B, Tate BN, Zhang H, Rosen BD, Van Tassell CP, Liu GE, Coarfa C, Ren YA, Waterland RA. Chang WJ, et al. Among authors: waterland ra. Genome Biol. 2024 Jul 15;25(1):185. doi: 10.1186/s13059-024-03307-6. Genome Biol. 2024. PMID: 39004763 Free PMC article.
DNA methylation at a nutritionally sensitive region of the PAX8 gene is associated with thyroid volume and function in Gambian children.
Candler T, Kessler NJ, Gunasekara CJ, Ward KA, James P, Laritsky E, Baker MS, Dyer R, Elango R, Jeffries D, Waterland RA, Moore SE, Ludgate M, Prentice AM, Silver MJ. Candler T, et al. Among authors: waterland ra. Sci Adv. 2021 Nov 5;7(45):eabj1561. doi: 10.1126/sciadv.abj1561. Epub 2021 Nov 5. Sci Adv. 2021. PMID: 34739318 Free PMC article.
83 results