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Page 1
SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.
Kim D, Fiske BP, Birsoy K, Freinkman E, Kami K, Possemato RL, Chudnovsky Y, Pacold ME, Chen WW, Cantor JR, Shelton LM, Gui DY, Kwon M, Ramkissoon SH, Ligon KL, Kang SW, Snuderl M, Vander Heiden MG, Sabatini DM. Kim D, et al. Among authors: cantor jr. Nature. 2015 Apr 16;520(7547):363-7. doi: 10.1038/nature14363. Epub 2015 Apr 8. Nature. 2015. PMID: 25855294 Free PMC article.
Cancer cell metabolism: one hallmark, many faces.
Cantor JR, Sabatini DM. Cantor JR, et al. Cancer Discov. 2012 Oct;2(10):881-98. doi: 10.1158/2159-8290.CD-12-0345. Epub 2012 Sep 25. Cancer Discov. 2012. PMID: 23009760 Free PMC article. Review.
Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition.
Shaul YD, Freinkman E, Comb WC, Cantor JR, Tam WL, Thiru P, Kim D, Kanarek N, Pacold ME, Chen WW, Bierie B, Possemato R, Reinhardt F, Weinberg RA, Yaffe MB, Sabatini DM. Shaul YD, et al. Among authors: cantor jr. Cell. 2014 Aug 28;158(5):1094-1109. doi: 10.1016/j.cell.2014.07.032. Cell. 2014. PMID: 25171410 Free PMC article.
Histidine catabolism is a major determinant of methotrexate sensitivity.
Kanarek N, Keys HR, Cantor JR, Lewis CA, Chan SH, Kunchok T, Abu-Remaileh M, Freinkman E, Schweitzer LD, Sabatini DM. Kanarek N, et al. Among authors: cantor jr. Nature. 2018 Jul;559(7715):632-636. doi: 10.1038/s41586-018-0316-7. Epub 2018 Jul 11. Nature. 2018. PMID: 29995852 Free PMC article.
Sestrin2 is a leucine sensor for the mTORC1 pathway.
Wolfson RL, Chantranupong L, Saxton RA, Shen K, Scaria SM, Cantor JR, Sabatini DM. Wolfson RL, et al. Among authors: cantor jr. Science. 2016 Jan 1;351(6268):43-8. doi: 10.1126/science.aab2674. Epub 2015 Oct 8. Science. 2016. PMID: 26449471 Free PMC article.
ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase.
Williams RT, Guarecuco R, Gates LA, Barrows D, Passarelli MC, Carey B, Baudrier L, Jeewajee S, La K, Prizer B, Malik S, Garcia-Bermudez J, Zhu XG, Cantor J, Molina H, Carroll T, Roeder RG, Abdel-Wahab O, Allis CD, Birsoy K. Williams RT, et al. Cell Metab. 2020 Apr 7;31(4):852-861.e6. doi: 10.1016/j.cmet.2020.03.008. Cell Metab. 2020. PMID: 32268116 Free PMC article.
36 results