Al-Rashood ST - Search Results

1

Synthesis, biological evaluation and 2D-QSAR study of halophenyl bis-hydrazones as antimicrobial and antitubercular agents.

Abdel-Aziz HA, Eldehna WM, Fares M, Al-Rashood ST, Al-Rashood KA, Abdel-Aziz MM, Soliman DH. Abdel-Aziz HA, et al. Int J Mol Sci. 2015 Apr 20;16(4):8719-43. doi: 10.3390/ijms16048719. Int J Mol Sci. 2015. PMID: 25903147 Free PMC article.

2

2-((Benzimidazol-2-yl)thio)-1-arylethan-1-ones: Synthesis, crystal study and cancer stem cells CD133 targeting potential.

Abdel-Aziz HA, Ghabbour HA, Eldehna WM, Al-Rashood ST, Al-Rashood KA, Fun HK, Al-Tahhan M, Al-Dhfyan A. Abdel-Aziz HA, et al. Eur J Med Chem. 2015 Nov 2;104:1-10. doi: 10.1016/j.ejmech.2015.09.023. Epub 2015 Sep 16. Eur J Med Chem. 2015. PMID: 26413725

3

Determination of apremilast in rat plasma by UPLC-MS/MS in ESI-negative mode to avoid adduct ions formation.

Iqbal M, Ezzeldin E, Al-Rashood ST, Imam F, Al-Rashood KA. Iqbal M, et al. Bioanalysis. 2016 Jul;8(14):1499-1508. doi: 10.4155/bio-2016-0098. Epub 2016 Jun 28. Bioanalysis. 2016. PMID: 27349803

4

Simple and Highly Sensitive UPLC-ESI-MS/MS Assay for Rapid Determination of Suvorexant in Plasma.

Iqbal M, Ezzeldin E, Khalil NY, Al-Rashood ST, Al-Rashood KA. Iqbal M, et al. J Anal Toxicol. 2017 Mar 1;41(2):114-120. doi: 10.1093/jat/bkw111. J Anal Toxicol. 2017. PMID: 28376227

5

Cancer stem cells CD133 inhibition and cytotoxicity of certain 3-phenylthiazolo[3,2-a]benzimidazoles: design, direct synthesis, crystal study and in vitro biological evaluation.

Al-Ansary GH, Eldehna WM, Ghabbour HA, Al-Rashood STA, Al-Rashood KA, Eladwy RA, Al-Dhfyan A, Kabil MM, Abdel-Aziz HA. Al-Ansary GH, et al. J Enzyme Inhib Med Chem. 2017 Dec;32(1):986-991. doi: 10.1080/14756366.2017.1347166. J Enzyme Inhib Med Chem. 2017. PMID: 28726519 Free PMC article.

6

Tumor-associated carbonic anhydrase isoform IX and XII inhibitory properties of certain isatin-bearing sulfonamides endowed with in vitro antitumor activity towards colon cancer.

Eldehna WM, Nocentini A, Al-Rashood ST, Hassan GS, Alkahtani HM, Almehizia AA, Reda AM, Abdel-Aziz HA, Supuran CT. Eldehna WM, et al. Bioorg Chem. 2018 Dec;81:425-432. doi: 10.1016/j.bioorg.2018.09.007. Epub 2018 Sep 7. Bioorg Chem. 2018. PMID: 30219719

7

Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents.

Eldehna WM, Abo-Ashour MF, Nocentini A, El-Haggar RS, Bua S, Bonardi A, Al-Rashood ST, Hassan GS, Gratteri P, Abdel-Aziz HA, Supuran CT. Eldehna WM, et al. Eur J Med Chem. 2019 Jan 15;162:147-160. doi: 10.1016/j.ejmech.2018.10.068. Epub 2018 Nov 2. Eur J Med Chem. 2019. PMID: 30445264

8

SLC-0111 enaminone analogs, 3/4-(3-aryl-3-oxopropenyl) aminobenzenesulfonamides, as novel selective subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform IX.

Eldehna WM, Abo-Ashour MF, Berrino E, Vullo D, Ghabbour HA, Al-Rashood ST, Hassan GS, Alkahtani HM, Almehizia AA, Alharbi A, Abdel-Aziz HA, Supuran CT. Eldehna WM, et al. Bioorg Chem. 2019 Mar;83:549-558. doi: 10.1016/j.bioorg.2018.11.014. Epub 2018 Nov 14. Bioorg Chem. 2019. PMID: 30471577

9

Type IIA - Type IIB protein tyrosine kinase inhibitors hybridization as an efficient approach for potent multikinase inhibitor development: Design, synthesis, anti-proliferative activity, multikinase inhibitory activity and molecular modeling of novel indolinone-based ureides and amides.

Eldehna WM, El Kerdawy AM, Al-Ansary GH, Al-Rashood ST, Ali MM, Mahmoud AE. Eldehna WM, et al. Eur J Med Chem. 2019 Feb 1;163:37-53. doi: 10.1016/j.ejmech.2018.11.061. Epub 2018 Nov 24. Eur J Med Chem. 2019. PMID: 30503942

10

Synthesis and in vitro anticancer activity of certain novel 1-(2-methyl-6-arylpyridin-3-yl)-3-phenylureas as apoptosis-inducing agents.

Eldehna WM, Hassan GS, Al-Rashood ST, Al-Warhi T, Altyar AE, Alkahtani HM, Almehizia AA, Abdel-Aziz HA. Eldehna WM, et al. J Enzyme Inhib Med Chem. 2019 Dec;34(1):322-332. doi: 10.1080/14756366.2018.1547286. J Enzyme Inhib Med Chem. 2019. PMID: 30722708 Free PMC article.

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