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Page 1
Altered Micafungin Pharmacokinetics in Intensive Care Unit Patients.
Lempers VJ, Schouten JA, Hunfeld NG, Colbers A, van Leeuwen HJ, Burger DM, Verweij PE, Pickkers P, Brüggemann RJ. Lempers VJ, et al. Among authors: van leeuwen hj. Antimicrob Agents Chemother. 2015 Aug;59(8):4403-9. doi: 10.1128/AAC.00623-15. Epub 2015 May 11. Antimicrob Agents Chemother. 2015. PMID: 25963988 Free PMC article. Clinical Trial.
High unbound flucloxacillin fraction in critically ill patients.
Wallenburg E, Ter Heine R, de Lange DW, van Leeuwen H, Schouten JA, Ten Oever J, Kolwijck E, Burger DM, Pickkers P, Gieling EM, de Maat MM, Frenzel T, Brüggemann RJ. Wallenburg E, et al. J Antimicrob Chemother. 2021 Nov 12;76(12):3220-3228. doi: 10.1093/jac/dkab314. J Antimicrob Chemother. 2021. PMID: 34463730 Free PMC article.
Pharmacokinetics of caspofungin in ICU patients.
Muilwijk EW, Schouten JA, van Leeuwen HJ, van Zanten AR, de Lange DW, Colbers A, Verweij PE, Burger DM, Pickkers P, Brüggemann RJ. Muilwijk EW, et al. Among authors: van leeuwen hj, van zanten ar. J Antimicrob Chemother. 2014 Dec;69(12):3294-9. doi: 10.1093/jac/dku313. Epub 2014 Aug 19. J Antimicrob Chemother. 2014. PMID: 25139840 Clinical Trial.
Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study.
De Bus L, Depuydt P, Steen J, Dhaese S, De Smet K, Tabah A, Akova M, Cotta MO, De Pascale G, Dimopoulos G, Fujitani S, Garnacho-Montero J, Leone M, Lipman J, Ostermann M, Paiva JA, Schouten J, Sjövall F, Timsit JF, Roberts JA, Zahar JR, Zand F, Zirpe K, De Waele JJ; DIANA study group. De Bus L, et al. Intensive Care Med. 2020 Jul;46(7):1404-1417. doi: 10.1007/s00134-020-06111-5. Epub 2020 Jun 9. Intensive Care Med. 2020. PMID: 32519003 Free PMC article.
Phenylephrine impairs host defence mechanisms to infection: a combined laboratory study in mice and translational human study.
Stolk RF, Reinema F, van der Pasch E, Schouwstra J, Bressers S, van Herwaarden AE, Gerretsen J, Schambergen R, Ruth M, van der Hoeven HG, van Leeuwen HJ, Pickkers P, Kox M. Stolk RF, et al. Among authors: van leeuwen hj. Br J Anaesth. 2021 Mar;126(3):652-664. doi: 10.1016/j.bja.2020.11.040. Epub 2021 Jan 20. Br J Anaesth. 2021. PMID: 33483132 Free article. Clinical Trial.
Temporal changes in the epidemiology, management, and outcome from acute respiratory distress syndrome in European intensive care units: a comparison of two large cohorts.
Sakr Y, François B, Solé-Violan J, Kotfis K, Jaschinski U, Estella A, Leone M, Jakob SM, Wittebole X, Fontes LE, de Melo Gurgel M, Midega T, Vincent JL, Ranieri VM; SOAP and ICON Investigators. Sakr Y, et al. Crit Care. 2021 Feb 25;25(1):87. doi: 10.1186/s13054-020-03455-8. Crit Care. 2021. PMID: 33632247 Free PMC article.
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