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Long-term tolerance to skin commensals is established neonatally through a specialized dendritic cell subgroup.
Weckel A, Dhariwala MO, Ly K, Tran VM, Ojewumi OT, Riggs JB, Gonzalez JR, Dwyer LR, Okoro JN, Leech JM, Bacino MS, Cho GD, Merana G, Anandasabapathy N, Kumamoto Y, Scharschmidt TC. Weckel A, et al. Among authors: anandasabapathy n. Immunity. 2023 Jun 13;56(6):1239-1254.e7. doi: 10.1016/j.immuni.2023.03.008. Epub 2023 Apr 6. Immunity. 2023. PMID: 37028427 Free PMC article.
Metabolic coordination between skin epithelium and type 17 immunity sustains chronic skin inflammation.
Subudhi I, Konieczny P, Prystupa A, Castillo RL, Sze-Tu E, Xing Y, Rosenblum D, Reznikov I, Sidhu I, Loomis C, Lu CP, Anandasabapathy N, Suárez-Fariñas M, Gudjonsson JE, Tsirigos A, Scher JU, Naik S. Subudhi I, et al. Among authors: anandasabapathy n. Immunity. 2024 Jul 9;57(7):1665-1680.e7. doi: 10.1016/j.immuni.2024.04.022. Epub 2024 May 20. Immunity. 2024. PMID: 38772365 Free PMC article.
Langerhans Cells Orchestrate TFH-Dependent Humoral Immunity.
Vardam T, Anandasabapathy N. Vardam T, et al. Among authors: anandasabapathy n. J Invest Dermatol. 2017 Sep;137(9):1826-1828. doi: 10.1016/j.jid.2017.06.014. J Invest Dermatol. 2017. PMID: 28843293 Free PMC article. Review.
PD-1 is requisite for skin TRM cell formation and specification by TGFβ.
Devi KSP, Wang E, Jaiswal A, Konieczny P, Kim TG, Nirschl CJ, Verma A, Liu Y, Milczanowski J, Christo SN, Gandolfo LC, Haitz K, Vardam TD, Wu P, King SL, Tse SW, Pradhan K, Jiang X, Tian T, Fuhlbrigge RC, Schmults CD, Clark RA, Kupper TS, Freeman GJ, Mackay LK, Naik S, Newell EW, Elemento O, Suarez-Farinas M, Anandasabapathy N. Devi KSP, et al. Among authors: anandasabapathy n. Nat Immunol. 2025 Aug;26(8):1339-1351. doi: 10.1038/s41590-025-02228-1. Epub 2025 Jul 29. Nat Immunol. 2025. PMID: 40730902 Free PMC article.
Immune Checkpoint Blockade and Skin Toxicity Pathogenesis.
Ma B, Anandasabapathy N. Ma B, et al. Among authors: anandasabapathy n. J Invest Dermatol. 2022 Mar;142(3 Pt B):951-959. doi: 10.1016/j.jid.2021.06.040. Epub 2021 Nov 26. J Invest Dermatol. 2022. PMID: 34844731 Free article. Review.
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