Distelhorst CW - Search Results

1

A synthetic peptide targeting the BH4 domain of Bcl-2 induces apoptosis in multiple myeloma and follicular lymphoma cells alone or in combination with agents targeting the BH3-binding pocket of Bcl-2.

Lavik AR, Zhong F, Chang MJ, Greenberg E, Choudhary Y, Smith MR, McColl KS, Pink J, Reu FJ, Matsuyama S, Distelhorst CW. Lavik AR, et al. Among authors: distelhorst cw. Oncotarget. 2015 Sep 29;6(29):27388-402. doi: 10.18632/oncotarget.4489. Oncotarget. 2015. PMID: 26317541 Free PMC article.

2

Bcl-2 differentially regulates Ca2+ signals according to the strength of T cell receptor activation.

Zhong F, Davis MC, McColl KS, Distelhorst CW. Zhong F, et al. Among authors: distelhorst cw. J Cell Biol. 2006 Jan 2;172(1):127-37. doi: 10.1083/jcb.200506189. J Cell Biol. 2006. PMID: 16391001 Free PMC article.

3

Induction of Ca²+-driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2-IP3 receptor interaction.

Zhong F, Harr MW, Bultynck G, Monaco G, Parys JB, De Smedt H, Rong YP, Molitoris JK, Lam M, Ryder C, Matsuyama S, Distelhorst CW. Zhong F, et al. Among authors: distelhorst cw. Blood. 2011 Mar 10;117(10):2924-34. doi: 10.1182/blood-2010-09-307405. Epub 2010 Dec 30. Blood. 2011. PMID: 21193695 Free PMC article.

4

Acidosis promotes Bcl-2 family-mediated evasion of apoptosis: involvement of acid-sensing G protein-coupled receptor Gpr65 signaling to Mek/Erk.

Ryder C, McColl K, Zhong F, Distelhorst CW. Ryder C, et al. Among authors: distelhorst cw. J Biol Chem. 2012 Aug 10;287(33):27863-75. doi: 10.1074/jbc.M112.384685. Epub 2012 Jun 8. J Biol Chem. 2012. PMID: 22685289 Free PMC article.

5

Feedback regulation mediated by Bcl-2 and DARPP-32 regulates inositol 1,4,5-trisphosphate receptor phosphorylation and promotes cell survival.

Chang MJ, Zhong F, Lavik AR, Parys JB, Berridge MJ, Distelhorst CW. Chang MJ, et al. Among authors: distelhorst cw. Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1186-91. doi: 10.1073/pnas.1323098111. Epub 2014 Jan 6. Proc Natl Acad Sci U S A. 2014. PMID: 24395794 Free PMC article.

6

Bcl-2 regulation of the inositol 1,4,5-trisphosphate receptor and calcium signaling in normal and malignant lymphocytes: potential new target for cancer treatment.

Greenberg EF, Lavik AR, Distelhorst CW. Greenberg EF, et al. Among authors: distelhorst cw. Biochim Biophys Acta. 2014 Oct;1843(10):2205-10. doi: 10.1016/j.bbamcr.2014.03.008. Epub 2014 Mar 15. Biochim Biophys Acta. 2014. PMID: 24642270 Free PMC article. Review.

7

Synergistic killing of human small cell lung cancer cells by the Bcl-2-inositol 1,4,5-trisphosphate receptor disruptor BIRD-2 and the BH3-mimetic ABT-263.

Greenberg EF, McColl KS, Zhong F, Wildey G, Dowlati A, Distelhorst CW. Greenberg EF, et al. Among authors: distelhorst cw. Cell Death Dis. 2015 Dec 31;6(12):e2034. doi: 10.1038/cddis.2015.355. Cell Death Dis. 2015. PMID: 26720343 Free PMC article.

8

Microarray analysis uncovers the induction of the proapoptotic BH3-only protein Bim in multiple models of glucocorticoid-induced apoptosis.

Wang Z, Malone MH, He H, McColl KS, Distelhorst CW. Wang Z, et al. Among authors: distelhorst cw. J Biol Chem. 2003 Jun 27;278(26):23861-7. doi: 10.1074/jbc.M301843200. Epub 2003 Apr 2. J Biol Chem. 2003. PMID: 12676946 Free article.

9

Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate.

Chen R, Valencia I, Zhong F, McColl KS, Roderick HL, Bootman MD, Berridge MJ, Conway SJ, Holmes AB, Mignery GA, Velez P, Distelhorst CW. Chen R, et al. Among authors: distelhorst cw. J Cell Biol. 2004 Jul 19;166(2):193-203. doi: 10.1083/jcb.200309146. J Cell Biol. 2004. PMID: 15263017 Free PMC article.

10

Dexamethasone-induced inositol 1,4,5-trisphosphate receptor elevation in murine lymphoma cells is not required for dexamethasone-mediated calcium elevation and apoptosis.

Davis MC, McColl KS, Zhong F, Wang Z, Malone MH, Distelhorst CW. Davis MC, et al. Among authors: distelhorst cw. J Biol Chem. 2008 Apr 18;283(16):10357-65. doi: 10.1074/jbc.M800269200. Epub 2008 Feb 13. J Biol Chem. 2008. PMID: 18272518 Free PMC article.

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