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Page 1
Long-term Multimodal Recording Reveals Epigenetic Adaptation Routes in Dormant Breast Cancer Cells.
Rosano D, Sofyali E, Dhiman H, Ghirardi C, Ivanoiu D, Heide T, Vingiani A, Bertolotti A, Pruneri G, Canale E, Dewhurst HF, Saha D, Slaven N, Barozzi I, Li T, Zemlyanskiy G, Phillips H, James C, Győrffy B, Lynn C, Cresswell GD, Rehman F, Noberini R, Bonaldi T, Sottoriva A, Magnani L. Rosano D, et al. Among authors: bonaldi t. Cancer Discov. 2024 May 1;14(5):866-889. doi: 10.1158/2159-8290.CD-23-1161. Cancer Discov. 2024. PMID: 38527495 Free PMC article.
Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide.
Russo M, Gualdrini F, Vallelonga V, Prosperini E, Noberini R, Pedretti S, Borriero C, Di Chiaro P, Polletti S, Imperato G, Marenda M, Ghirardi C, Bedin F, Cuomo A, Rodighiero S, Bonaldi T, Mitro N, Ghisletti S, Natoli G. Russo M, et al. Among authors: bonaldi t. Mol Cell. 2024 Mar 7;84(5):967-980.e10. doi: 10.1016/j.molcel.2023.12.033. Epub 2024 Jan 18. Mol Cell. 2024. PMID: 38242130 Free PMC article.
Unveiling the role of PUS7-mediated pseudouridylation in host protein interactions specific for the SARS-CoV-2 RNA genome.
Giambruno R, Zacco E, Ugolini C, Vandelli A, Mulroney L, D'Onghia M, Giuliani B, Criscuolo E, Castelli M, Clementi N, Clementi M, Mancini N, Bonaldi T, Gustincich S, Leonardi T, Tartaglia GG, Nicassio F. Giambruno R, et al. Among authors: bonaldi t. Mol Ther Nucleic Acids. 2023 Oct 25;34:102052. doi: 10.1016/j.omtn.2023.102052. eCollection 2023 Dec 12. Mol Ther Nucleic Acids. 2023. PMID: 38028201 Free PMC article.
Hyperacetylated histone H4 is a source of carbon contributing to lipid synthesis.
Charidemou E, Noberini R, Ghirardi C, Georgiou P, Marcou P, Theophanous A, Strati K, Keun H, Behrends V, Bonaldi T, Kirmizis A. Charidemou E, et al. Among authors: bonaldi t. EMBO J. 2024 Apr;43(7):1187-1213. doi: 10.1038/s44318-024-00053-0. Epub 2024 Feb 21. EMBO J. 2024. PMID: 38383863 Free PMC article.
Substantial histone reduction modulates genomewide nucleosomal occupancy and global transcriptional output.
Celona B, Weiner A, Di Felice F, Mancuso FM, Cesarini E, Rossi RL, Gregory L, Baban D, Rossetti G, Grianti P, Pagani M, Bonaldi T, Ragoussis J, Friedman N, Camilloni G, Bianchi ME, Agresti A. Celona B, et al. Among authors: bonaldi t. PLoS Biol. 2011 Jun;9(6):e1001086. doi: 10.1371/journal.pbio.1001086. Epub 2011 Jun 28. PLoS Biol. 2011. PMID: 21738444 Free PMC article.
Cell reprogramming requires silencing of a core subset of polycomb targets.
Fragola G, Germain PL, Laise P, Cuomo A, Blasimme A, Gross F, Signaroldi E, Bucci G, Sommer C, Pruneri G, Mazzarol G, Bonaldi T, Mostoslavsky G, Casola S, Testa G. Fragola G, et al. Among authors: bonaldi t. PLoS Genet. 2013;9(2):e1003292. doi: 10.1371/journal.pgen.1003292. Epub 2013 Feb 28. PLoS Genet. 2013. PMID: 23468641 Free PMC article.
134 results