MacLean AL - Search Results

1

Mathematical and Statistical Techniques for Systems Medicine: The Wnt Signaling Pathway as a Case Study.

MacLean AL, Harrington HA, Stumpf MP, Byrne HM. MacLean AL, et al. Methods Mol Biol. 2016;1386:405-39. doi: 10.1007/978-1-4939-3283-2_18. Methods Mol Biol. 2016. PMID: 26677193 Review.

2

Population dynamics of normal and leukaemia stem cells in the haematopoietic stem cell niche show distinct regimes where leukaemia will be controlled.

MacLean AL, Lo Celso C, Stumpf MP. MacLean AL, et al. J R Soc Interface. 2013 Jan 24;10(81):20120968. doi: 10.1098/rsif.2012.0968. Print 2013 Apr 6. J R Soc Interface. 2013. PMID: 23349436 Free PMC article.

3

The ecology in the hematopoietic stem cell niche determines the clinical outcome in chronic myeloid leukemia.

MacLean AL, Filippi S, Stumpf MP. MacLean AL, et al. Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):3883-8. doi: 10.1073/pnas.1317072111. Epub 2014 Feb 24. Proc Natl Acad Sci U S A. 2014. PMID: 24567385 Free PMC article.

4

Parameter-free methods distinguish Wnt pathway models and guide design of experiments.

MacLean AL, Rosen Z, Byrne HM, Harrington HA. MacLean AL, et al. Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):2652-7. doi: 10.1073/pnas.1416655112. Epub 2015 Feb 17. Proc Natl Acad Sci U S A. 2015. PMID: 25730853 Free PMC article.

5

Cellular population dynamics control the robustness of the stem cell niche.

MacLean AL, Kirk PD, Stumpf MP. MacLean AL, et al. Biol Open. 2015 Oct 9;4(11):1420-6. doi: 10.1242/bio.013714. Biol Open. 2015. PMID: 26453624 Free PMC article.

6

Feedback mechanisms control coexistence in a stem cell model of acute myeloid leukaemia.

Crowell HL, MacLean AL, Stumpf MP. Crowell HL, et al. Among authors: maclean al. J Theor Biol. 2016 Jul 21;401:43-53. doi: 10.1016/j.jtbi.2016.04.002. Epub 2016 Apr 27. J Theor Biol. 2016. PMID: 27130539 Free PMC article.

7

Systematic tracking of altered haematopoiesis during sporozoite-mediated malaria development reveals multiple response points.

Vainieri ML, Blagborough AM, MacLean AL, Haltalli ML, Ruivo N, Fletcher HA, Stumpf MP, Sinden RE, Celso CL. Vainieri ML, et al. Among authors: maclean al. Open Biol. 2016 Jun;6(6):160038. doi: 10.1098/rsob.160038. Open Biol. 2016. PMID: 27335321 Free PMC article.

8

Concise Review: Stem Cell Population Biology: Insights from Hematopoiesis.

MacLean AL, Lo Celso C, Stumpf MP. MacLean AL, et al. Stem Cells. 2017 Jan;35(1):80-88. doi: 10.1002/stem.2508. Epub 2016 Oct 26. Stem Cells. 2017. PMID: 27671750 Review.

9

Epithelial-Mesenchymal Transition in Metastatic Cancer Cell Populations Affects Tumor Dormancy in a Simple Mathematical Model.

MacLean AL, Harrington HA, Stumpf MPH, Hansen MDH. MacLean AL, et al. Biomedicines. 2014 Dec 9;2(4):384-402. doi: 10.3390/biomedicines2040384. Biomedicines. 2014. PMID: 28548077 Free PMC article.

10

Single Cell Phenotyping Reveals Heterogeneity Among Hematopoietic Stem Cells Following Infection.

MacLean AL, Smith MA, Liepe J, Sim A, Khorshed R, Rashidi NM, Scherf N, Krinner A, Roeder I, Lo Celso C, Stumpf MPH. MacLean AL, et al. Stem Cells. 2017 Nov;35(11):2292-2304. doi: 10.1002/stem.2692. Epub 2017 Sep 24. Stem Cells. 2017. PMID: 28833970

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