Mecsas J - Search Results

1

Beyond Antibiotics: New Therapeutic Approaches for Bacterial Infections.

Hauser AR, Mecsas J, Moir DT. Hauser AR, et al. Clin Infect Dis. 2016 Jul 1;63(1):89-95. doi: 10.1093/cid/ciw200. Epub 2016 Mar 29. Clin Infect Dis. 2016. PMID: 27025826 Free PMC article.

2

Mutations in the Pseudomonas aeruginosa needle protein gene pscF confer resistance to phenoxyacetamide inhibitors of the type III secretion system.

Bowlin NO, Williams JD, Knoten CA, Torhan MC, Tashjian TF, Li B, Aiello D, Mecsas J, Hauser AR, Peet NP, Bowlin TL, Moir DT. Bowlin NO, et al. Antimicrob Agents Chemother. 2014;58(4):2211-20. doi: 10.1128/AAC.02795-13. Epub 2014 Jan 27. Antimicrob Agents Chemother. 2014. PMID: 24468789 Free PMC article.

3

Bacterial Secretion Systems: An Overview.

Green ER, Mecsas J. Green ER, et al. Microbiol Spectr. 2016 Feb;4(1):10.1128/microbiolspec.VMBF-0012-2015. doi: 10.1128/microbiolspec.VMBF-0012-2015. Microbiol Spectr. 2016. PMID: 26999395 Free PMC article. Review.

4

Inhibition of the Injectisome and Flagellar Type III Secretion Systems by INP1855 Impairs Pseudomonas aeruginosa Pathogenicity and Inflammasome Activation.

Anantharajah A, Faure E, Buyck JM, Sundin C, Lindmark T, Mecsas J, Yahr TL, Tulkens PM, Mingeot-Leclercq MP, Guery B, Van Bambeke F. Anantharajah A, et al. J Infect Dis. 2016 Oct 1;214(7):1105-16. doi: 10.1093/infdis/jiw295. Epub 2016 Jul 13. J Infect Dis. 2016. PMID: 27412581

5

A Structure-Function-Inhibition Analysis of the Pseudomonas aeruginosa Type III Secretion Needle Protein PscF.

Moir DT, Bowlin NO, Berube BJ, Yabut J, Mills DM, Nguyen GT, Aron ZD, Williams JD, Mecsas J, Hauser AR, Bowlin TL. Moir DT, et al. J Bacteriol. 2020 Aug 25;202(18):e00055-20. doi: 10.1128/JB.00055-20. Print 2020 Aug 25. J Bacteriol. 2020. PMID: 32601072 Free PMC article.

6

Klebsiella pneumoniae: Going on the Offense with a Strong Defense.

Paczosa MK, Mecsas J. Paczosa MK, et al. Microbiol Mol Biol Rev. 2016 Jun 15;80(3):629-61. doi: 10.1128/MMBR.00078-15. Print 2016 Sep. Microbiol Mol Biol Rev. 2016. PMID: 27307579 Free PMC article. Review.

7

Promises and Challenges of the Type Three Secretion System Injectisome as an Antivirulence Target.

Fasciano AC, Shaban L, Mecsas J. Fasciano AC, et al. EcoSal Plus. 2019 Feb;8(2):10.1128/ecosalplus.ESP-0032-2018. doi: 10.1128/ecosalplus.ESP-0032-2018. EcoSal Plus. 2019. PMID: 30706846 Free PMC article. Review.

8

The presence of professional phagocytes dictates the number of host cells targeted for Yop translocation during infection.

Durand EA, Maldonado-Arocho FJ, Castillo C, Walsh RL, Mecsas J. Durand EA, et al. Cell Microbiol. 2010 Aug;12(8):1064-82. doi: 10.1111/j.1462-5822.2010.01451.x. Epub 2010 Feb 9. Cell Microbiol. 2010. PMID: 20148898 Free PMC article.

9

Identification of MrtAB, an ABC transporter specifically required for Yersinia pseudotuberculosis to colonize the mesenteric lymph nodes.

Crimmins GT, Mohammadi S, Green ER, Bergman MA, Isberg RR, Mecsas J. Crimmins GT, et al. PLoS Pathog. 2012;8(8):e1002828. doi: 10.1371/journal.ppat.1002828. Epub 2012 Aug 2. PLoS Pathog. 2012. PMID: 22876175 Free PMC article.

10

Detection of Cells Translocated with Yersinia Yops in Infected Tissues Using β-Lactamase Fusions.

Nguyen GT, McCabe AL, Fasciano AC, Mecsas J. Nguyen GT, et al. Methods Mol Biol. 2019;2010:117-139. doi: 10.1007/978-1-4939-9541-7_9. Methods Mol Biol. 2019. PMID: 31177435 Free PMC article.

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