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Page 1
Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor.
Rothhammer V, Mascanfroni ID, Bunse L, Takenaka MC, Kenison JE, Mayo L, Chao CC, Patel B, Yan R, Blain M, Alvarez JI, Kébir H, Anandasabapathy N, Izquierdo G, Jung S, Obholzer N, Pochet N, Clish CB, Prinz M, Prat A, Antel J, Quintana FJ. Rothhammer V, et al. Among authors: anandasabapathy n. Nat Med. 2016 Jun;22(6):586-97. doi: 10.1038/nm.4106. Epub 2016 May 9. Nat Med. 2016. PMID: 27158906 Free PMC article.
Long-term tolerance to skin commensals is established neonatally through a specialized dendritic cell subgroup.
Weckel A, Dhariwala MO, Ly K, Tran VM, Ojewumi OT, Riggs JB, Gonzalez JR, Dwyer LR, Okoro JN, Leech JM, Bacino MS, Cho GD, Merana G, Anandasabapathy N, Kumamoto Y, Scharschmidt TC. Weckel A, et al. Among authors: anandasabapathy n. Immunity. 2023 Jun 13;56(6):1239-1254.e7. doi: 10.1016/j.immuni.2023.03.008. Epub 2023 Apr 6. Immunity. 2023. PMID: 37028427 Free PMC article.
Metabolic coordination between skin epithelium and type 17 immunity sustains chronic skin inflammation.
Subudhi I, Konieczny P, Prystupa A, Castillo RL, Sze-Tu E, Xing Y, Rosenblum D, Reznikov I, Sidhu I, Loomis C, Lu CP, Anandasabapathy N, Suárez-Fariñas M, Gudjonsson JE, Tsirigos A, Scher JU, Naik S. Subudhi I, et al. Among authors: anandasabapathy n. Immunity. 2024 Jul 9;57(7):1665-1680.e7. doi: 10.1016/j.immuni.2024.04.022. Epub 2024 May 20. Immunity. 2024. PMID: 38772365 Free PMC article.
IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment.
Nirschl CJ, Suárez-Fariñas M, Izar B, Prakadan S, Dannenfelser R, Tirosh I, Liu Y, Zhu Q, Devi KSP, Carroll SL, Chau D, Rezaee M, Kim TG, Huang R, Fuentes-Duculan J, Song-Zhao GX, Gulati N, Lowes MA, King SL, Quintana FJ, Lee YS, Krueger JG, Sarin KY, Yoon CH, Garraway L, Regev A, Shalek AK, Troyanskaya O, Anandasabapathy N. Nirschl CJ, et al. Among authors: anandasabapathy n. Cell. 2017 Jun 29;170(1):127-141.e15. doi: 10.1016/j.cell.2017.06.016. Cell. 2017. PMID: 28666115 Free PMC article.
A molecular single-cell lung atlas of lethal COVID-19.
Melms JC, Biermann J, Huang H, Wang Y, Nair A, Tagore S, Katsyv I, Rendeiro AF, Amin AD, Schapiro D, Frangieh CJ, Luoma AM, Filliol A, Fang Y, Ravichandran H, Clausi MG, Alba GA, Rogava M, Chen SW, Ho P, Montoro DT, Kornberg AE, Han AS, Bakhoum MF, Anandasabapathy N, Suárez-Fariñas M, Bakhoum SF, Bram Y, Borczuk A, Guo XV, Lefkowitch JH, Marboe C, Lagana SM, Del Portillo A, Tsai EJ, Zorn E, Markowitz GS, Schwabe RF, Schwartz RE, Elemento O, Saqi A, Hibshoosh H, Que J, Izar B. Melms JC, et al. Among authors: anandasabapathy n. Nature. 2021 Jul;595(7865):114-119. doi: 10.1038/s41586-021-03569-1. Epub 2021 Apr 29. Nature. 2021. PMID: 33915568 Free PMC article.
Id1 suppresses anti-tumour immune responses and promotes tumour progression by impairing myeloid cell maturation.
Papaspyridonos M, Matei I, Huang Y, do Rosario Andre M, Brazier-Mitouart H, Waite JC, Chan AS, Kalter J, Ramos I, Wu Q, Williams C, Wolchok JD, Chapman PB, Peinado H, Anandasabapathy N, Ocean AJ, Kaplan RN, Greenfield JP, Bromberg J, Skokos D, Lyden D. Papaspyridonos M, et al. Among authors: anandasabapathy n. Nat Commun. 2015 Apr 29;6:6840. doi: 10.1038/ncomms7840. Nat Commun. 2015. PMID: 25924227 Free PMC article.
PD-1 is requisite for skin TRM cell formation and specification by TGFβ.
Devi KSP, Wang E, Jaiswal A, Konieczny P, Kim TG, Nirschl CJ, Verma A, Liu Y, Milczanowski J, Christo SN, Gandolfo LC, Haitz K, Vardam TD, Wu P, King SL, Tse SW, Pradhan K, Jiang X, Tian T, Fuhlbrigge RC, Schmults CD, Clark RA, Kupper TS, Freeman GJ, Mackay LK, Naik S, Newell EW, Elemento O, Suarez-Farinas M, Anandasabapathy N. Devi KSP, et al. Among authors: anandasabapathy n. Nat Immunol. 2025 Aug;26(8):1339-1351. doi: 10.1038/s41590-025-02228-1. Epub 2025 Jul 29. Nat Immunol. 2025. PMID: 40730902 Free PMC article.
48 results