Chitraju C - Search Results

1

Identification and characterization of a novel DGAT1 missense mutation associated with congenital diarrhea.

Gluchowski NL, Chitraju C, Picoraro JA, Mejhert N, Pinto S, Xin W, Kamin DS, Winter HS, Chung WK, Walther TC, Farese RV Jr. Gluchowski NL, et al. Among authors: chitraju c. J Lipid Res. 2017 Jun;58(6):1230-1237. doi: 10.1194/jlr.P075119. Epub 2017 Apr 3. J Lipid Res. 2017. PMID: 28373485 Free PMC article.

2

High confidence proteomic analysis of yeast LDs identifies additional droplet proteins and reveals connections to dolichol synthesis and sterol acetylation.

Currie E, Guo X, Christiano R, Chitraju C, Kory N, Harrison K, Haas J, Walther TC, Farese RV Jr. Currie E, et al. Among authors: chitraju c. J Lipid Res. 2014 Jul;55(7):1465-77. doi: 10.1194/jlr.M050229. Epub 2014 May 27. J Lipid Res. 2014. PMID: 24868093 Free PMC article.

3

Seipin is required for converting nascent to mature lipid droplets.

Wang H, Becuwe M, Housden BE, Chitraju C, Porras AJ, Graham MM, Liu XN, Thiam AR, Savage DB, Agarwal AK, Garg A, Olarte MJ, Lin Q, Fröhlich F, Hannibal-Bach HK, Upadhyayula S, Perrimon N, Kirchhausen T, Ejsing CS, Walther TC, Farese RV. Wang H, et al. Among authors: chitraju c. Elife. 2016 Aug 26;5:e16582. doi: 10.7554/eLife.16582. Elife. 2016. PMID: 27564575 Free PMC article.

4

Mice lacking lipid droplet-associated hydrolase, a gene linked to human prostate cancer, have normal cholesterol ester metabolism.

Kory N, Grond S, Kamat SS, Li Z, Krahmer N, Chitraju C, Zhou P, Fröhlich F, Semova I, Ejsing C, Zechner R, Cravatt BF, Farese RV Jr, Walther TC. Kory N, et al. Among authors: chitraju c. J Lipid Res. 2017 Jan;58(1):226-235. doi: 10.1194/jlr.M072538. Epub 2016 Nov 11. J Lipid Res. 2017. PMID: 27836991 Free PMC article.

5

Triglyceride Synthesis by DGAT1 Protects Adipocytes from Lipid-Induced ER Stress during Lipolysis.

Chitraju C, Mejhert N, Haas JT, Diaz-Ramirez LG, Grueter CA, Imbriglio JE, Pinto S, Koliwad SK, Walther TC, Farese RV Jr. Chitraju C, et al. Cell Metab. 2017 Aug 1;26(2):407-418.e3. doi: 10.1016/j.cmet.2017.07.012. Cell Metab. 2017. PMID: 28768178 Free PMC article.

6

Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids.

Piccolis M, Bond LM, Kampmann M, Pulimeno P, Chitraju C, Jayson CBK, Vaites LP, Boland S, Lai ZW, Gabriel KR, Elliott SD, Paulo JA, Harper JW, Weissman JS, Walther TC, Farese RV Jr. Piccolis M, et al. Among authors: chitraju c. Mol Cell. 2019 Apr 4;74(1):32-44.e8. doi: 10.1016/j.molcel.2019.01.036. Epub 2019 Mar 4. Mol Cell. 2019. PMID: 30846318 Free PMC article.

7

The triglyceride synthesis enzymes DGAT1 and DGAT2 have distinct and overlapping functions in adipocytes.

Chitraju C, Walther TC, Farese RV Jr. Chitraju C, et al. J Lipid Res. 2019 Jun;60(6):1112-1120. doi: 10.1194/jlr.M093112. Epub 2019 Apr 1. J Lipid Res. 2019. PMID: 30936184 Free PMC article.

8

Hepatocyte Deletion of Triglyceride-Synthesis Enzyme Acyl CoA: Diacylglycerol Acyltransferase 2 Reduces Steatosis Without Increasing Inflammation or Fibrosis in Mice.

Gluchowski NL, Gabriel KR, Chitraju C, Bronson RT, Mejhert N, Boland S, Wang K, Lai ZW, Farese RV Jr, Walther TC. Gluchowski NL, et al. Among authors: chitraju c. Hepatology. 2019 Dec;70(6):1972-1985. doi: 10.1002/hep.30765. Epub 2019 Jun 26. Hepatology. 2019. PMID: 31081165 Free PMC article.

9

Endogenous levels of 1-O-acylceramides increase upon acidic ceramidase deficiency and decrease due to loss of Dgat1 in a tissue-dependent manner.

Bayerle A, Marsching C, Rabionet M, Dworski S, Kamani MA, Chitraju C, Gluchowski NL, Gabriel KR, Herzer S, Jennemann R, Levade T, Medin JA, Sandhoff R. Bayerle A, et al. Among authors: chitraju c. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Sep;1865(9):158741. doi: 10.1016/j.bbalip.2020.158741. Epub 2020 May 28. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32474112

10

Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis.

Chitraju C, Fischer AW, Farese RV Jr, Walther TC. Chitraju C, et al. Cell Rep. 2020 Nov 3;33(5):108348. doi: 10.1016/j.celrep.2020.108348. Cell Rep. 2020. PMID: 33147469 Free PMC article.

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