Hruby VJ - Search Results

1

Design and synthesis of conformationally constrained somatostatin analogues with high potency and specificity for mu opioid receptors.

Pelton JT, Kazmierski W, Gulya K, Yamamura HI, Hruby VJ. Pelton JT, et al. Among authors: hruby vj. J Med Chem. 1986 Nov;29(11):2370-5. doi: 10.1021/jm00161a037. J Med Chem. 1986. PMID: 2878079

2

Design and synthesis of highly potent and selective cyclic dynorphin A analogues.

Kawasaki AM, Knapp RJ, Kramer TH, Wire WS, Vasquez OS, Yamamura HI, Burks TF, Hruby VJ. Kawasaki AM, et al. Among authors: hruby vj. J Med Chem. 1990 Jul;33(7):1874-9. doi: 10.1021/jm00169a007. J Med Chem. 1990. PMID: 1972964

3

[D-Pen2,D-Pen5]enkephalin analogues with increased affinity and selectivity for delta opioid receptors.

Toth G, Kramer TH, Knapp R, Lui G, Davis P, Burks TF, Yamamura HI, Hruby VJ. Toth G, et al. Among authors: hruby vj. J Med Chem. 1990 Jan;33(1):249-53. doi: 10.1021/jm00163a041. J Med Chem. 1990. PMID: 2153205

4

Synthesis of highly mu and delta opioid receptor selective peptides containing a photoaffinity group.

Landis G, Lui G, Shook JE, Yamamura HI, Burks TF, Hruby VJ. Landis G, et al. Among authors: hruby vj. J Med Chem. 1989 Mar;32(3):638-43. doi: 10.1021/jm00123a023. J Med Chem. 1989. PMID: 2537426

5

Conformationally restricted analogs of somatostatin with high mu-opiate receptor specificity.

Pelton JT, Gulya K, Hruby VJ, Duckles SP, Yamamura HI. Pelton JT, et al. Among authors: hruby vj. Proc Natl Acad Sci U S A. 1985 Jan;82(1):236-9. doi: 10.1073/pnas.82.1.236. Proc Natl Acad Sci U S A. 1985. PMID: 2857488 Free PMC article.

6

Cyclic somatostatin octapeptide analogues with high affinity and selectivity toward mu opioid receptors.

Gulya K, Pelton JT, Hruby VJ, Yamamura HI. Gulya K, et al. Among authors: hruby vj. Life Sci. 1986 Jun 16;38(24):2221-9. doi: 10.1016/0024-3205(86)90574-6. Life Sci. 1986. PMID: 2872570

7

Design and synthesis of somatostatin analogues with topographical properties that lead to highly potent and specific mu opioid receptor antagonists with greatly reduced binding at somatostatin receptors.

Kazmierski W, Wire WS, Lui GK, Knapp RJ, Shook JE, Burks TF, Yamamura HI, Hruby VJ. Kazmierski W, et al. Among authors: hruby vj. J Med Chem. 1988 Nov;31(11):2170-7. doi: 10.1021/jm00119a019. J Med Chem. 1988. PMID: 2903246

8

Design of cyclic deltorphins and dermenkephalins with a disulfide bridge leads to analogues with high selectivity for delta-opioid receptors.

Misicka A, Lipkowski AW, Horvath R, Davis P, Yamamura HI, Porreca F, Hruby VJ. Misicka A, et al. Among authors: hruby vj. J Med Chem. 1994 Jan 7;37(1):141-5. doi: 10.1021/jm00027a017. J Med Chem. 1994. PMID: 8289187

9

Cyclic enkephalin analogues with exceptional potency and selectivity for delta-opioid receptors.

Hruby VJ, Bartosz-Bechowski H, Davis P, Slaninova J, Zalewska T, Stropova D, Porreca F, Yamamura HI. Hruby VJ, et al. J Med Chem. 1997 Nov 21;40(24):3957-62. doi: 10.1021/jm9704762. J Med Chem. 1997. PMID: 9397176

10

Ring substituted and other conformationally constrained tyrosine analogues of [D-Pen2,D-Pen5]enkephalin with delta opioid receptor selectivity.

Toth G, Russell KC, Landis G, Kramer TH, Fang L, Knapp R, Davis P, Burks TF, Yamamura HI, Hruby VJ. Toth G, et al. Among authors: hruby vj. J Med Chem. 1992 Jun 26;35(13):2384-91. doi: 10.1021/jm00091a006. J Med Chem. 1992. PMID: 1320122

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