Yu X - Search Results

1

Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice.

Newman JC, Covarrubias AJ, Zhao M, Yu X, Gut P, Ng CP, Huang Y, Haldar S, Verdin E. Newman JC, et al. Among authors: yu x. Cell Metab. 2017 Sep 5;26(3):547-557.e8. doi: 10.1016/j.cmet.2017.08.004. Cell Metab. 2017. PMID: 28877458 Free PMC article.

2

Tau reduction affects excitatory and inhibitory neurons differently, reduces excitation/inhibition ratios, and counteracts network hypersynchrony.

Chang CW, Evans MD, Yu X, Yu GQ, Mucke L. Chang CW, et al. Among authors: yu gq, yu x. Cell Rep. 2021 Oct 19;37(3):109855. doi: 10.1016/j.celrep.2021.109855. Cell Rep. 2021. PMID: 34686344 Free PMC article.

3

Neuronal levels and sequence of tau modulate the power of brain rhythms.

Das M, Maeda S, Hu B, Yu GQ, Guo W, Lopez I, Yu X, Tai C, Wang X, Mucke L. Das M, et al. Among authors: yu gq, yu x. Neurobiol Dis. 2018 Sep;117:181-188. doi: 10.1016/j.nbd.2018.05.020. Epub 2018 May 31. Neurobiol Dis. 2018. PMID: 29859869

4

Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer's disease mutations but not by inhibition of BACE1.

Johnson ECB, Ho K, Yu GQ, Das M, Sanchez PE, Djukic B, Lopez I, Yu X, Gill M, Zhang W, Paz JT, Palop JJ, Mucke L. Johnson ECB, et al. Among authors: yu gq, yu x. Mol Neurodegener. 2020 Sep 14;15(1):53. doi: 10.1186/s13024-020-00393-5. Mol Neurodegener. 2020. PMID: 32921309 Free PMC article.

5

Tau Reduction Prevents Key Features of Autism in Mouse Models.

Tai C, Chang CW, Yu GQ, Lopez I, Yu X, Wang X, Guo W, Mucke L. Tai C, et al. Among authors: yu gq, yu x. Neuron. 2020 May 6;106(3):421-437.e11. doi: 10.1016/j.neuron.2020.01.038. Epub 2020 Mar 2. Neuron. 2020. PMID: 32126198 Free PMC article.

6

Phenotypic Differences between the Alzheimer's Disease-Related hAPP-J20 Model and Heterozygous Zbtb20 Knock-Out Mice.

Gulbranson DR, Ho K, Yu GQ, Yu X, Das M, Shao E, Kim D, Zhang WJ, Choudhary K, Thomas R, Mucke L. Gulbranson DR, et al. Among authors: yu gq, yu x. eNeuro. 2021 May 13;8(3):ENEURO.0089-21.2021. doi: 10.1523/ENEURO.0089-21.2021. Print 2021 May-Jun. eNeuro. 2021. PMID: 33833046 Free PMC article.

7

Interdependence of neural network dysfunction and microglial alterations in Alzheimer's disease-related models.

Das M, Mao W, Shao E, Tamhankar S, Yu GQ, Yu X, Ho K, Wang X, Wang J, Mucke L. Das M, et al. Among authors: yu gq, yu x. iScience. 2021 Oct 7;24(11):103245. doi: 10.1016/j.isci.2021.103245. eCollection 2021 Nov 19. iScience. 2021. PMID: 34755090 Free PMC article.

8

Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse models.

Das M, Mao W, Voskobiynyk Y, Necula D, Lew I, Petersen C, Zahn A, Yu GQ, Yu X, Smith N, Sayed FA, Gan L, Paz JT, Mucke L. Das M, et al. Among authors: yu gq, yu x. Neurobiol Dis. 2023 Oct 1;186:106263. doi: 10.1016/j.nbd.2023.106263. Epub 2023 Aug 15. Neurobiol Dis. 2023. PMID: 37591465 Free PMC article.

9

TAU ablation in excitatory neurons and postnatal TAU knockdown reduce epilepsy, SUDEP, and autism behaviors in a Dravet syndrome model.

Shao E, Chang CW, Li Z, Yu X, Ho K, Zhang M, Wang X, Simms J, Lo I, Speckart J, Holtzman J, Yu GQ, Roberson ED, Mucke L. Shao E, et al. Among authors: yu gq, yu x. Sci Transl Med. 2022 Apr 27;14(642):eabm5527. doi: 10.1126/scitranslmed.abm5527. Epub 2022 Apr 27. Sci Transl Med. 2022. PMID: 35476595 Free PMC article.

10

Evidence from multicenter clinical studies and humanized mouse models indicates that glomerular mesangial IgA2 deposition contributes to the pathogenesis of IgA nephropathy.

Li R, Ma Y, Xie X, Qin A, Chen Q, Zhang Y, Tian W, Yu X, Li G, Jin J, Zhang H, Lv J. Li R, et al. Among authors: yu x. Kidney Int. 2026 Mar 13:S0085-2538(26)00161-4. doi: 10.1016/j.kint.2026.02.018. Online ahead of print. Kidney Int. 2026. PMID: 41833637

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