Sim MK - Search Results

1

Bioavailability of Orally Administered Des-Aspartate-Angiotensin I in Human Subjects.

Lee KO, Tian EF, Cai MH, Wang H, Chan YH, Sim MK. Lee KO, et al. Among authors: sim mk. Drugs R D. 2018 Mar;18(1):51-54. doi: 10.1007/s40268-017-0218-4. Drugs R D. 2018. PMID: 29168127 Free PMC article. Clinical Trial.

2

Des-aspartate-angiotensin-I and angiotensin IV improve glucose tolerance and insulin signalling in diet-induced hyperglycaemic mice.

Wong YC, Sim MK, Lee KO. Wong YC, et al. Among authors: sim mk. Biochem Pharmacol. 2011 Nov 1;82(9):1198-208. doi: 10.1016/j.bcp.2011.07.080. Epub 2011 Jul 23. Biochem Pharmacol. 2011. PMID: 21803028

3

Des-aspartate-angiotensin I causes specific release of PGE2 and PGI2 in HUVEC via the angiotensin AT1 receptor and biased agonism.

Wen Q, Lee KO, Sim SZ, Xu XG, Sim MK. Wen Q, et al. Among authors: sim mk, sim sz. Eur J Pharmacol. 2015 Dec 5;768:173-81. doi: 10.1016/j.ejphar.2015.10.051. Epub 2015 Oct 31. Eur J Pharmacol. 2015. PMID: 26524410

4

A Single Dose-Escalation Study to Evaluate the Safety and Pharmacokinetics of Orally Administered Des-Aspartate Angiotensin I in Healthy Subjects.

Lee KO, Khoo CM, Chowbay B, Chan YH, Sim MK. Lee KO, et al. Among authors: sim mk. Drugs R D. 2016 Dec;16(4):317-326. doi: 10.1007/s40268-016-0143-y. Drugs R D. 2016. PMID: 27681888 Free PMC article. Clinical Trial.

5

Author's Reply to Srinivas: "A Single Dose-Escalation Study to Evaluate the Safety and Pharmacokinetics of Orally Administered Des-Aspartate Angiotensin I in Healthy Subjects".

Sim MK, Lee KO. Sim MK, et al. Drugs R D. 2017 Mar;17(1):243-244. doi: 10.1007/s40268-016-0156-6. Drugs R D. 2017. PMID: 27905016 Free PMC article. No abstract available.

6

Des-Aspartate-Angiotensin I Attenuates Mortality of Mice Exposed to Gamma Radiation via a Novel Mechanism of Action.

Wang H, Sethi G, Loke WK, Sim MK. Wang H, et al. Among authors: sim mk. PLoS One. 2015 Sep 17;10(9):e0138009. doi: 10.1371/journal.pone.0138009. eCollection 2015. PLoS One. 2015. PMID: 26378927 Free PMC article.

7

Des-aspartate-angiotensin I exerts hypoglycemic action via glucose transporter-4 translocation in type 2 diabetic KKAy mice and GK rats.

Sim MK, Xu XG, Wong YC, Sim SZ, Lee KO. Sim MK, et al. Among authors: sim sz. Endocrinology. 2007 Dec;148(12):5925-32. doi: 10.1210/en.2007-0606. Epub 2007 Sep 6. Endocrinology. 2007. PMID: 17823251

8

Protective actions of des-aspartate-angiotensin I in mice model of CEES-induced lung intoxication.

Ng ET, Sim MK, Loke WK. Ng ET, et al. Among authors: sim mk. J Appl Toxicol. 2011 Aug;31(6):568-78. doi: 10.1002/jat.1599. Epub 2010 Nov 9. J Appl Toxicol. 2011. PMID: 21061449

9

Des-aspartate-angiotensin I, a novel angiotensin AT(1) receptor drug.

Sim MK. Sim MK. Eur J Pharmacol. 2015 Aug 5;760:36-41. doi: 10.1016/j.ejphar.2015.04.004. Epub 2015 Apr 17. Eur J Pharmacol. 2015. PMID: 25891368 Review.

10

Effects of des-aspartate-angiotensin I on myocardial ischemia-reperfusion injury in rats.

Wen Q, Sim MK. Wen Q, et al. Among authors: sim mk. Eur J Pharmacol. 2011 May 11;658(2-3):193-9. doi: 10.1016/j.ejphar.2011.02.014. Epub 2011 Mar 1. Eur J Pharmacol. 2011. PMID: 21371467

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