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Genes controlling the activation of natural killer lymphocytes are epigenetically remodeled in intestinal cells from germ-free mice.
Poupeau A, Garde C, Sulek K, Citirikkaya K, Treebak JT, Arumugam M, Simar D, Olofsson LE, Bäckhed F, Barrès R. Poupeau A, et al. Among authors: simar d. FASEB J. 2019 Feb;33(2):2719-2731. doi: 10.1096/fj.201800787R. Epub 2018 Oct 10. FASEB J. 2019. PMID: 30303739 Free PMC article.

At the gene level, we found an enrichment for differentially methylated regions proximal to genes regulating the cytotoxicity of NK cells (false-discovery rate < 8.9E(-6)), notably genes regulating the cross-talk between NK cells and target cells, such as members of the NK gro

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At the gene level, we found an enrichment for differentially methylated regions proximal to genes regulating the cytotoxicity of NK cells (f …
65 results