Comparison between germline and somatic loss-of-function RNF43 mutations reveals different genotype-phenotype associations and provides insights into the genetic mechanisms of colorectal tumourigenesis.
Palles C, Freeman-Mills L, Arbe-Barnes E, Feeley N, Chegwidden L, Curley H, Galavotti S, Woolley C, Cheadle J, Mouradov D, Sieber O, Salatino S, Thorn S, Goel A, Fernandez-Tajes J, Omwenga S, Biswas S, Maughan T, Leedham SJ; S:CORT Consortium; UK Colorectal Cancer Genomics Consortium; CORGI Consortium; WGS500 Consortium; Koelzer VH, Wang LM, Arnold R, East JE, Tomlinson I.
Palles C, et al.
Gut. 2025 Dec 24:gutjnl-2025-337030. doi: 10.1136/gutjnl-2025-337030. Online ahead of print.
Gut. 2025.
PMID: 41443981
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