Lesser CF - Search Results

1

Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes.

Sandstrom A, Mitchell PS, Goers L, Mu EW, Lesser CF, Vance RE. Sandstrom A, et al. Among authors: lesser cf. Science. 2019 Apr 5;364(6435):eaau1330. doi: 10.1126/science.aau1330. Epub 2019 Mar 14. Science. 2019. PMID: 30872533 Free PMC article.

2

NAIP-NLRC4-deficient mice are susceptible to shigellosis.

Mitchell PS, Roncaioli JL, Turcotte EA, Goers L, Chavez RA, Lee AY, Lesser CF, Rauch I, Vance RE. Mitchell PS, et al. Among authors: lesser cf. Elife. 2020 Oct 19;9:e59022. doi: 10.7554/eLife.59022. Elife. 2020. PMID: 33074100 Free PMC article.

3

A host metabolite promotes Salmonella survival.

Lynch JP, Lesser CF. Lynch JP, et al. Among authors: lesser cf. Science. 2021 Jan 22;371(6527):344-345. doi: 10.1126/science.abf8414. Science. 2021. PMID: 33479138 No abstract available.

4

Emerging strategies for engineering Escherichia coli Nissle 1917-based therapeutics.

Lynch JP, Goers L, Lesser CF. Lynch JP, et al. Among authors: lesser cf. Trends Pharmacol Sci. 2022 Sep;43(9):772-786. doi: 10.1016/j.tips.2022.02.002. Epub 2022 Feb 26. Trends Pharmacol Sci. 2022. PMID: 35232591 Free PMC article. Review.

5

Shigella IpaH9.8 limits GBP1-dependent LPS release from intracytosolic bacteria to suppress caspase-4 activation.

Goers L, Kim K, Stedman TC, Canning PJ, Mou X, Ernst NH, Coers J, Lesser CF. Goers L, et al. Among authors: lesser cf. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15):e2218469120. doi: 10.1073/pnas.2218469120. Epub 2023 Apr 4. Proc Natl Acad Sci U S A. 2023. PMID: 37014865 Free PMC article.

6

Shigella OspF blocks rapid p38-dependent priming of the NAIP-NLRC4 inflammasome.

Turcotte EA, Kim K, Eislmayr KD, Goers L, Mitchell PS, Lesser CF, Vance RE. Turcotte EA, et al. Among authors: lesser cf. bioRxiv [Preprint]. 2025 Feb 2:2025.02.01.636075. doi: 10.1101/2025.02.01.636075. bioRxiv. 2025. PMID: 39975412 Free PMC article. Preprint.

7

Synthetic bottom-up approach reveals the complex interplay of Shigella effectors in regulation of epithelial cell death.

Mou X, Souter S, Du J, Reeves AZ, Lesser CF. Mou X, et al. Among authors: lesser cf. Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):6452-6457. doi: 10.1073/pnas.1801310115. Epub 2018 Jun 4. Proc Natl Acad Sci U S A. 2018. PMID: 29866849 Free PMC article.

8

The GBP1 microcapsule interferes with IcsA-dependent septin cage assembly around Shigella flexneri.

Kutsch M, González-Prieto C, Lesser CF, Coers J. Kutsch M, et al. Among authors: lesser cf. Pathog Dis. 2021 Apr 24;79(5):ftab023. doi: 10.1093/femspd/ftab023. Pathog Dis. 2021. PMID: 33885766 Free PMC article.

9

The Shigella Spp. Type III Effector Protein OspB Is a Cysteine Protease.

Wood TE, Westervelt KA, Yoon JM, Eshleman HD, Levy R, Burnes H, Slade DJ, Lesser CF, Goldberg MB. Wood TE, et al. Among authors: lesser cf. mBio. 2022 Jun 28;13(3):e0127022. doi: 10.1128/mbio.01270-22. Epub 2022 May 31. mBio. 2022. PMID: 35638611 Free PMC article.

10

Macrophages orchestrate elimination of Shigella from the intestinal epithelial cell niche via TLR-induced IL-12 and IFN-γ.

Eislmayr KD, Langner C, Liu FL, Yuvaraj S, Babirye JP, Roncaioli JL, Vickery JM, Barton GM, Lesser CF, Vance RE. Eislmayr KD, et al. Among authors: lesser cf. bioRxiv [Preprint]. 2025 Jan 22:2025.01.20.633976. doi: 10.1101/2025.01.20.633976. bioRxiv. 2025. Update in: Cell Host Microbe. 2025 Sep 10;33(9):1535-1549.e7. doi: 10.1016/j.chom.2025.08.001. PMID: 39896533 Free PMC article. Updated. Preprint.

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