Williams DC Jr - Search Results

1

Methyl-CpG-binding domain as a protein interaction partner in promoter regulation and neurodevelopment through evolutionary expanded entanglement.

Bilinovich SM, Chhetri SB, Mitchell JT, Leighton GO, Jdanov V, Zieba JK, Cook TW, Engel KL, Vaughan RM, Bhatti H, Heeringa SL, Wilstermann AM, Vanderweele S, Das AS, Sherry EC, Duncan SA, Uhl KL, Hinds DC, Mackiewicz M, Meadows SK, Newberry KM, Partridge EC, Cline SG, Shepard CJ, Smith DC, Bradley A, Vogt D, Campbell DB, Pozzo-Miller L, Bupp CP, Goodyke AJ, Rajasekaran S, Knickmeyer RC, Blair B, Krawczyk CM, Triche TJ Jr, Myers RM, Mendenhall EM, Williams DC Jr, Prokop JW. Bilinovich SM, et al. Among authors: williams dc jr. Am J Physiol Cell Physiol. 2025 Sep 1;329(3):C848-C867. doi: 10.1152/ajpcell.00749.2024. Epub 2025 Jul 25. Am J Physiol Cell Physiol. 2025. PMID: 40712661 Free article.

2

Exploring the bistable equilibrium of methylated CpG DNA recognition by the MBD2 protein.

Volkenandt S, Belyaeva J, Li T, Elgeti M, Metzler R, Imhof P, Williams DC Jr, Helabad MB. Volkenandt S, et al. Among authors: williams dc jr. bioRxiv [Preprint]. 2025 Jun 30:2025.06.30.662303. doi: 10.1101/2025.06.30.662303. bioRxiv. 2025. PMID: 40631181 Free PMC article. Preprint.

3

The role of multivalency in the association of the eight twenty-one protein 2 (ETO2) with the nucleosome remodeling and deacetylase (NuRD) complex.

Dan-Dukor G, Shang S, Leighton GO, Travis CR, Schwochert TD, Agrawal P, Ajasa O, Li T, Waters ML, Ginder GD, Williams DC Jr. Dan-Dukor G, et al. Among authors: williams dc jr. Nucleic Acids Res. 2025 May 22;53(10):gkaf439. doi: 10.1093/nar/gkaf439. Nucleic Acids Res. 2025. PMID: 40421803 Free PMC article.

4

Editorial overview: New perspectives on the structure and dynamics of protein-nucleic acid interactions.

Iwahara J, Williams DC Jr. Iwahara J, et al. Among authors: williams dc jr. Curr Opin Struct Biol. 2025 Feb;90:102957. doi: 10.1016/j.sbi.2024.102957. Epub 2024 Dec 3. Curr Opin Struct Biol. 2025. PMID: 39631258 No abstract available.

5

Analysis of the complex between MBD2 and the histone deacetylase core of NuRD reveals key interactions critical for gene silencing.

Leighton GO, Shang S, Hageman S, Ginder GD, Williams DC Jr. Leighton GO, et al. Among authors: williams dc jr. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2307287120. doi: 10.1073/pnas.2307287120. Epub 2023 Aug 8. Proc Natl Acad Sci U S A. 2023. PMID: 37552759 Free PMC article.

6

MBD2a-NuRD binds to the methylated γ-globin gene promoter and uniquely forms a complex required for silencing of HbF expression.

Shang S, Li X, Azzo A, Truong T, Dozmorov M, Lyons C, Manna AK, Williams DC Jr, Ginder GD. Shang S, et al. Among authors: williams dc jr. Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2302254120. doi: 10.1073/pnas.2302254120. Epub 2023 Jun 12. Proc Natl Acad Sci U S A. 2023. PMID: 37307480 Free PMC article.

7

DNALI1 interacts with the MEIG1/PACRG complex within the manchette and is required for proper sperm flagellum assembly in mice.

Yap YT, Li W, Huang Q, Zhou Q, Zhang D, Sheng Y, Mladenovic-Lucas L, Yee SP, Orwig KE, Granneman JG, Williams DC Jr, Hess RA, Toure A, Zhang Z. Yap YT, et al. Among authors: williams dc jr. Elife. 2023 Apr 21;12:e79620. doi: 10.7554/eLife.79620. Elife. 2023. PMID: 37083624 Free PMC article.

8

Evaluation of acyllysine isostere interactions with the aromatic pocket of the AF9 YEATS domain.

Travis CR, Francis DY, Williams DC Jr, Waters ML. Travis CR, et al. Among authors: williams dc jr. Protein Sci. 2023 Jan;32(1):e4533. doi: 10.1002/pro.4533. Protein Sci. 2023. PMID: 36482045 Free PMC article.

9

Densely methylated DNA traps Methyl-CpG-binding domain protein 2 but permits free diffusion by Methyl-CpG-binding domain protein 3.

Leighton GO, Irvin EM, Kaur P, Liu M, You C, Bhattaram D, Piehler J, Riehn R, Wang H, Pan H, Williams DC Jr. Leighton GO, et al. Among authors: williams dc jr. J Biol Chem. 2022 Oct;298(10):102428. doi: 10.1016/j.jbc.2022.102428. Epub 2022 Aug 28. J Biol Chem. 2022. PMID: 36037972 Free PMC article.

10

The Ancient and Evolved Mouse Sperm-Associated Antigen 6 Genes Have Different Biologic Functions In Vivo.

Yap YT, Li W, Zhou Q, Haj-Diab S, Chowdhury DD, Vaishnav A, Harding P, Williams DC Jr, Edwards BF, Strauss JF 3rd, Zhang Z. Yap YT, et al. Among authors: williams dc jr. Cells. 2022 Jan 20;11(3):336. doi: 10.3390/cells11030336. Cells. 2022. PMID: 35159146 Free PMC article.

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