Couce A - Search Results

1

Mutation bias and GC content shape antimutator invasions.

Couce A, Tenaillon O. Couce A, et al. Nat Commun. 2019 Jul 15;10(1):3114. doi: 10.1038/s41467-019-11217-6. Nat Commun. 2019. PMID: 31308380 Free PMC article.

2

The rule of declining adaptability in microbial evolution experiments.

Couce A, Tenaillon OA. Couce A, et al. Front Genet. 2015 Mar 11;6:99. doi: 10.3389/fgene.2015.00099. eCollection 2015. Front Genet. 2015. PMID: 25815007 Free PMC article.

3

Mutator genomes decay, despite sustained fitness gains, in a long-term experiment with bacteria.

Couce A, Caudwell LV, Feinauer C, Hindré T, Feugeas JP, Weigt M, Lenski RE, Schneider D, Tenaillon O. Couce A, et al. Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9026-E9035. doi: 10.1073/pnas.1705887114. Epub 2017 Oct 10. Proc Natl Acad Sci U S A. 2017. PMID: 29073099 Free PMC article.

4

Flux, toxicity, and expression costs generate complex genetic interactions in a metabolic pathway.

Kemble H, Eisenhauer C, Couce A, Chapron A, Magnan M, Gautier G, Le Nagard H, Nghe P, Tenaillon O. Kemble H, et al. Among authors: couce a. Sci Adv. 2020 Jun 3;6(23):eabb2236. doi: 10.1126/sciadv.abb2236. eCollection 2020 Jun. Sci Adv. 2020. PMID: 32537514 Free PMC article.

5

Changing fitness effects of mutations through long-term bacterial evolution.

Couce A, Limdi A, Magnan M, Owen SV, Herren CM, Lenski RE, Tenaillon O, Baym M. Couce A, et al. Science. 2024 Jan 26;383(6681):eadd1417. doi: 10.1126/science.add1417. Epub 2024 Jan 26. Science. 2024. PMID: 38271521

6

The evolution of robustness and fragility during long-term bacterial adaptation.

Chihoub D, Pintard C, Lenski RE, Tenaillon O, Couce A. Chihoub D, et al. Among authors: couce a. Proc Natl Acad Sci U S A. 2025 Apr 22;122(16):e2501901122. doi: 10.1073/pnas.2501901122. Epub 2025 Apr 15. Proc Natl Acad Sci U S A. 2025. PMID: 40232797 Free PMC article.

7

Mutational spectrum drives the rise of mutator bacteria.

Couce A, Guelfo JR, Blázquez J. Couce A, et al. PLoS Genet. 2013;9(1):e1003167. doi: 10.1371/journal.pgen.1003167. Epub 2013 Jan 10. PLoS Genet. 2013. PMID: 23326242 Free PMC article.

8

Bypass of genetic constraints during mutator evolution to antibiotic resistance.

Couce A, Rodríguez-Rojas A, Blázquez J. Couce A, et al. Proc Biol Sci. 2015 Apr 7;282(1804):20142698. doi: 10.1098/rspb.2014.2698. Proc Biol Sci. 2015. PMID: 25716795 Free PMC article.

9

Determinants of Genetic Diversity of Spontaneous Drug Resistance in Bacteria.

Couce A, Rodríguez-Rojas A, Blázquez J. Couce A, et al. Genetics. 2016 Jul;203(3):1369-80. doi: 10.1534/genetics.115.185355. Epub 2016 May 10. Genetics. 2016. PMID: 27182949 Free PMC article.

10

Mutualism breakdown underpins evolutionary rescue in an obligate cross-feeding bacterial consortium.

Melero-Jiménez IJ, Sorokin Y, Merlin A, Li J, Couce A, Friedman J. Melero-Jiménez IJ, et al. Among authors: couce a. Nat Commun. 2025 Apr 12;16(1):3482. doi: 10.1038/s41467-025-58742-1. Nat Commun. 2025. PMID: 40216843 Free PMC article.

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