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Fancl-mutant mice reveal central role of monoubiquitination in Fanconi anemia and a model for therapeutic gene editing.
Liu L, Glaser A, Isiaku AI, Fairfax K, Casolari DA, Ristovski A, Murphy VJ, van Twest S, Henrikus SS, Heraud-Farlow J, Granger E, Novakovic S, Monks O'Byrne SF, Tsui V, Conyers R, Gonda TJ, Crismani W, D'Andrea RJ, Heierhorst J, Deans AJ. Liu L, et al. Among authors: henrikus ss. Blood Adv. 2025 Nov 19:bloodadvances.2025017217. doi: 10.1182/bloodadvances.2025017217. Online ahead of print. Blood Adv. 2025. PMID: 41259745
Structural basis of Fanconi anemia pathway activation by FANCM.
Bythell-Douglas R, van Twest S, Abbouche L, Dunn E, Coulthard RJ, Briggs DC, Murphy V, Zhang X, Tan W, Henrikus SS, Qian D, Wu Y, Wolf J, Rigoreau L, Shakeel S, Chapman KL, McDonald NQ, Deans AJ. Bythell-Douglas R, et al. Among authors: henrikus ss. EMBO J. 2025 Jul;44(14):4013-4036. doi: 10.1038/s44318-025-00468-3. Epub 2025 May 30. EMBO J. 2025. PMID: 40447800 Free PMC article.
Unwinding of a eukaryotic origin of replication visualized by cryo-EM.
Henrikus SS, Gross MH, Willhoft O, Pühringer T, Lewis JS, McClure AW, Greiwe JF, Palm G, Nans A, Diffley JFX, Costa A. Henrikus SS, et al. Nat Struct Mol Biol. 2024 Aug;31(8):1265-1276. doi: 10.1038/s41594-024-01280-z. Epub 2024 May 17. Nat Struct Mol Biol. 2024. PMID: 38760633 Free PMC article.
19 results