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Lutein reverses hyperglycemia-mediated blockage of Nrf2 translocation by modulating the activation of intracellular protein kinases in retinal pigment epithelial (ARPE-19) cells.

Shivarudrappa AH, Ponesakki G. Shivarudrappa AH, et al. J Cell Commun Signal. 2020 Jun;14(2):207-221. doi: 10.1007/s12079-019-00539-1. Epub 2019 Dec 9. J Cell Commun Signal. 2020. PMID: 31820335 Free PMC article.

Lutein activates downstream signaling pathways of unfolded protein response in hyperglycemic ARPE-19 cells.

Shivarudrappa AH, Sharan K, Ponesakki G. Shivarudrappa AH, et al. Eur J Pharmacol. 2022 Jan 5;914:174663. doi: 10.1016/j.ejphar.2021.174663. Epub 2021 Dec 1. Eur J Pharmacol. 2022. PMID: 34861209

Differential tumor immune microenvironment coupled with tumor progression or tumor eradication in HPV-antigen expressing squamous cell carcinoma (SCC) models.

Shivarudrappa AH, John J, Vashisht M, Ge H, Liu S, Chen J, Siddoway K, Dong R, Chen Z, Wang JH. Shivarudrappa AH, et al. Front Immunol. 2024 Jul 11;15:1405318. doi: 10.3389/fimmu.2024.1405318. eCollection 2024. Front Immunol. 2024. PMID: 39055715 Free PMC article.

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