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Mutant p53 on the Path to Metastasis.
Tang Q, Su Z, Gu W, Rustgi AK. Tang Q, et al. Among authors: rustgi ak. Trends Cancer. 2020 Jan;6(1):62-73. doi: 10.1016/j.trecan.2019.11.004. Epub 2019 Dec 16. Trends Cancer. 2020. PMID: 31952783 Free PMC article. Review.
Mutant p53 regulates Survivin to foster lung metastasis.
Tang Q, Efe G, Chiarella AM, Leung J, Chen M, Yamazoe T, Su Z, Pitarresi JR, Li J, Islam M, Karakasheva T, Klein-Szanto AJ, Pan S, Hu J, Natsugoe S, Gu W, Stanger BZ, Wong KK, Diehl JA, Bass AJ, Nakagawa H, Murphy ME, Rustgi AK. Tang Q, et al. Among authors: rustgi ak. Genes Dev. 2021 Apr 1;35(7-8):528-541. doi: 10.1101/gad.340505.120. Epub 2021 Mar 18. Genes Dev. 2021. PMID: 33737385 Free PMC article.
IL-6 Mediates Cross-Talk between Tumor Cells and Activated Fibroblasts in the Tumor Microenvironment.
Karakasheva TA, Lin EW, Tang Q, Qiao E, Waldron TJ, Soni M, Klein-Szanto AJ, Sahu V, Basu D, Ohashi S, Baba K, Giaccone ZT, Walker SR, Frank DA, Wileyto EP, Long Q, Dunagin MC, Raj A, Diehl JA, Wong KK, Bass AJ, Rustgi AK. Karakasheva TA, et al. Among authors: rustgi ak. Cancer Res. 2018 Sep 1;78(17):4957-4970. doi: 10.1158/0008-5472.CAN-17-2268. Epub 2018 Jul 5. Cancer Res. 2018. PMID: 29976575 Free PMC article.
EMT, MET, Plasticity, and Tumor Metastasis.
Bakir B, Chiarella AM, Pitarresi JR, Rustgi AK. Bakir B, et al. Among authors: rustgi ak. Trends Cell Biol. 2020 Oct;30(10):764-776. doi: 10.1016/j.tcb.2020.07.003. Epub 2020 Aug 13. Trends Cell Biol. 2020. PMID: 32800658 Free PMC article. Review.
Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration.
Giroux V, Lento AA, Islam M, Pitarresi JR, Kharbanda A, Hamilton KE, Whelan KA, Long A, Rhoades B, Tang Q, Nakagawa H, Lengner CJ, Bass AJ, Wileyto EP, Klein-Szanto AJ, Wang TC, Rustgi AK. Giroux V, et al. Among authors: rustgi ak. J Clin Invest. 2017 Jun 1;127(6):2378-2391. doi: 10.1172/JCI88941. Epub 2017 May 8. J Clin Invest. 2017. PMID: 28481227 Free PMC article.
PTHrP Drives Pancreatic Cancer Growth and Metastasis and Reveals a New Therapeutic Vulnerability.
Pitarresi JR, Norgard RJ, Chiarella AM, Suzuki K, Bakir B, Sahu V, Li J, Zhao J, Marchand B, Wengyn MD, Hsieh A, Kim IK, Zhang A, Sellin K, Lee V, Takano S, Miyahara Y, Ohtsuka M, Maitra A, Notta F, Kremer R, Stanger BZ, Rustgi AK. Pitarresi JR, et al. Among authors: rustgi ak. Cancer Discov. 2021 Jul;11(7):1774-1791. doi: 10.1158/2159-8290.CD-20-1098. Epub 2021 Feb 15. Cancer Discov. 2021. PMID: 33589425 Free PMC article.
Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors.
Ohashi S, Natsuizaka M, Wong GS, Michaylira CZ, Grugan KD, Stairs DB, Kalabis J, Vega ME, Kalman RA, Nakagawa M, Klein-Szanto AJ, Herlyn M, Diehl JA, Rustgi AK, Nakagawa H. Ohashi S, et al. Among authors: rustgi ak. Cancer Res. 2010 May 15;70(10):4174-84. doi: 10.1158/0008-5472.CAN-09-4614. Epub 2010 Apr 27. Cancer Res. 2010. PMID: 20424117 Free PMC article.
413 results