Lin YT - Search Results

1

Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes.

Blanchard JW, Bula M, Davila-Velderrain J, Akay LA, Zhu L, Frank A, Victor MB, Bonner JM, Mathys H, Lin YT, Ko T, Bennett DA, Cam HP, Kellis M, Tsai LH. Blanchard JW, et al. Among authors: lin yt. Nat Med. 2020 Jun;26(6):952-963. doi: 10.1038/s41591-020-0886-4. Epub 2020 Jun 8. Nat Med. 2020. PMID: 32514169 Free PMC article.

2

Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior.

Nott A, Cheng J, Gao F, Lin YT, Gjoneska E, Ko T, Minhas P, Zamudio AV, Meng J, Zhang F, Jin P, Tsai LH. Nott A, et al. Among authors: lin yt. Nat Neurosci. 2016 Nov;19(11):1497-1505. doi: 10.1038/nn.4347. Epub 2016 Jul 18. Nat Neurosci. 2016. PMID: 27428650 Free PMC article.

3

Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes.

Raja WK, Mungenast AE, Lin YT, Ko T, Abdurrob F, Seo J, Tsai LH. Raja WK, et al. Among authors: lin yt. PLoS One. 2016 Sep 13;11(9):e0161969. doi: 10.1371/journal.pone.0161969. eCollection 2016. PLoS One. 2016. PMID: 27622770 Free PMC article.

4

Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia.

Seo J, Kritskiy O, Watson LA, Barker SJ, Dey D, Raja WK, Lin YT, Ko T, Cho S, Penney J, Silva MC, Sheridan SD, Lucente D, Gusella JF, Dickerson BC, Haggarty SJ, Tsai LH. Seo J, et al. Among authors: lin yt. J Neurosci. 2017 Oct 11;37(41):9917-9924. doi: 10.1523/JNEUROSCI.0621-17.2017. Epub 2017 Sep 14. J Neurosci. 2017. PMID: 28912154 Free PMC article.

5

APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types.

Lin YT, Seo J, Gao F, Feldman HM, Wen HL, Penney J, Cam HP, Gjoneska E, Raja WK, Cheng J, Rueda R, Kritskiy O, Abdurrob F, Peng Z, Milo B, Yu CJ, Elmsaouri S, Dey D, Ko T, Yankner BA, Tsai LH. Lin YT, et al. Neuron. 2018 Jun 27;98(6):1141-1154.e7. doi: 10.1016/j.neuron.2018.05.008. Epub 2018 May 31. Neuron. 2018. PMID: 29861287 Free PMC article.

6

APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types.

Lin YT, Seo J, Gao F, Feldman HM, Wen HL, Penney J, Cam HP, Gjoneska E, Raja WK, Cheng J, Rueda R, Kritskiy O, Abdurrob F, Peng Z, Milo B, Yu CJ, Elmsaouri S, Dey D, Ko T, Yankner BA, Tsai LH. Lin YT, et al. Neuron. 2018 Jun 27;98(6):1294. doi: 10.1016/j.neuron.2018.06.011. Neuron. 2018. PMID: 29953873 Free PMC article. No abstract available.

7

REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer's Disease.

Meyer K, Feldman HM, Lu T, Drake D, Lim ET, Ling KH, Bishop NA, Pan Y, Seo J, Lin YT, Su SC, Church GM, Tsai LH, Yankner BA. Meyer K, et al. Among authors: lin yt. Cell Rep. 2019 Jan 29;26(5):1112-1127.e9. doi: 10.1016/j.celrep.2019.01.023. Cell Rep. 2019. PMID: 30699343 Free PMC article.

8

PICALM Rescues Endocytic Defects Caused by the Alzheimer's Disease Risk Factor APOE4.

Narayan P, Sienski G, Bonner JM, Lin YT, Seo J, Baru V, Haque A, Milo B, Akay LA, Graziosi A, Freyzon Y, Landgraf D, Hesse WR, Valastyan J, Barrasa MI, Tsai LH, Lindquist S. Narayan P, et al. Among authors: lin yt. Cell Rep. 2020 Oct 6;33(1):108224. doi: 10.1016/j.celrep.2020.108224. Cell Rep. 2020. PMID: 33027662 Free PMC article.

9

Author Correction: Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes.

Blanchard JW, Bula M, Davila-Velderrain J, Akay LA, Zhu L, Frank A, Victor MB, Bonner JM, Mathys H, Lin YT, Ko T, Bennett DA, Cam HP, Kellis M, Tsai LH. Blanchard JW, et al. Among authors: lin yt. Nat Med. 2021 Feb;27(2):356. doi: 10.1038/s41591-021-01250-8. Nat Med. 2021. PMID: 33514950 No abstract available.

10

APOE4-carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and Aβ generation.

Lee SI, Jeong W, Lim H, Cho S, Lee H, Jang Y, Cho J, Bae S, Lin YT, Tsai LH, Moon DW, Seo J. Lee SI, et al. Among authors: lin yt. Stem Cell Reports. 2021 Sep 14;16(9):2128-2137. doi: 10.1016/j.stemcr.2021.07.017. Epub 2021 Aug 26. Stem Cell Reports. 2021. PMID: 34450034 Free PMC article.

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