Cantor SB - Search Results

1

FANCJ compensates for RAP80 deficiency and suppresses genomic instability induced by interstrand cross-links.

Awate S, Sommers JA, Datta A, Nayak S, Bellani MA, Yang O, Dunn CA, Nicolae CM, Moldovan GL, Seidman MM, Cantor SB, Brosh RM. Awate S, et al. Among authors: cantor sb. Nucleic Acids Res. 2020 Sep 18;48(16):9161-9180. doi: 10.1093/nar/gkaa660. Nucleic Acids Res. 2020. PMID: 32797166 Free PMC article.

2

Analysis of the DNA substrate specificity of the human BACH1 helicase associated with breast cancer.

Gupta R, Sharma S, Sommers JA, Jin Z, Cantor SB, Brosh RM Jr. Gupta R, et al. Among authors: cantor sb. J Biol Chem. 2005 Jul 8;280(27):25450-60. doi: 10.1074/jbc.M501995200. Epub 2005 May 5. J Biol Chem. 2005. PMID: 15878853 Free article.

3

Inhibition of BACH1 (FANCJ) helicase by backbone discontinuity is overcome by increased motor ATPase or length of loading strand.

Gupta R, Sharma S, Doherty KM, Sommers JA, Cantor SB, Brosh RM Jr. Gupta R, et al. Among authors: cantor sb. Nucleic Acids Res. 2006;34(22):6673-83. doi: 10.1093/nar/gkl964. Epub 2006 Dec 1. Nucleic Acids Res. 2006. PMID: 17145708 Free PMC article.

4

The FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cells.

Peng M, Litman R, Xie J, Sharma S, Brosh RM Jr, Cantor SB. Peng M, et al. Among authors: cantor sb. EMBO J. 2007 Jul 11;26(13):3238-49. doi: 10.1038/sj.emboj.7601754. Epub 2007 Jun 21. EMBO J. 2007. PMID: 17581638 Free PMC article.

5

FANCJ (BACH1) helicase forms DNA damage inducible foci with replication protein A and interacts physically and functionally with the single-stranded DNA-binding protein.

Gupta R, Sharma S, Sommers JA, Kenny MK, Cantor SB, Brosh RM Jr. Gupta R, et al. Among authors: cantor sb. Blood. 2007 Oct 1;110(7):2390-8. doi: 10.1182/blood-2006-11-057273. Epub 2007 Jun 27. Blood. 2007. PMID: 17596542 Free PMC article.

6

BRCA-FA pathway as a target for anti-tumor drugs.

Litman R, Gupta R, Brosh RM Jr, Cantor SB. Litman R, et al. Among authors: cantor sb. Anticancer Agents Med Chem. 2008 May;8(4):426-30. doi: 10.2174/187152008784220285. Anticancer Agents Med Chem. 2008. PMID: 18473727 Free PMC article. Review.

7

FANCJ uses its motor ATPase to destabilize protein-DNA complexes, unwind triplexes, and inhibit RAD51 strand exchange.

Sommers JA, Rawtani N, Gupta R, Bugreev DV, Mazin AV, Cantor SB, Brosh RM Jr. Sommers JA, et al. Among authors: cantor sb. J Biol Chem. 2009 Mar 20;284(12):7505-17. doi: 10.1074/jbc.M809019200. Epub 2009 Jan 16. J Biol Chem. 2009. PMID: 19150983 Free PMC article.

8

Targeting the FANCJ-BRCA1 interaction promotes a switch from recombination to poleta-dependent bypass.

Xie J, Litman R, Wang S, Peng M, Guillemette S, Rooney T, Cantor SB. Xie J, et al. Among authors: cantor sb. Oncogene. 2010 Apr 29;29(17):2499-508. doi: 10.1038/onc.2010.18. Epub 2010 Feb 22. Oncogene. 2010. PMID: 20173781 Free PMC article.

9

Assessing the link between BACH1/FANCJ and MLH1 in DNA crosslink repair.

Cantor SB, Xie J. Cantor SB, et al. Environ Mol Mutagen. 2010 Jul;51(6):500-7. doi: 10.1002/em.20568. Environ Mol Mutagen. 2010. PMID: 20658644 Review.

10

An MLH1 mutation links BACH1/FANCJ to colon cancer, signaling, and insight toward directed therapy.

Xie J, Guillemette S, Peng M, Gilbert C, Buermeyer A, Cantor SB. Xie J, et al. Among authors: cantor sb. Cancer Prev Res (Phila). 2010 Nov;3(11):1409-16. doi: 10.1158/1940-6207.CAPR-10-0118. Epub 2010 Oct 26. Cancer Prev Res (Phila). 2010. PMID: 20978114 Free PMC article.

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