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Page 1
SALL4 is a CRL3REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma.
Lospinoso Severini L, Loricchio E, Navacci S, Basili I, Alfonsi R, Bernardi F, Moretti M, Conenna M, Cucinotta A, Coni S, Petroni M, De Smaele E, Giannini G, Maroder M, Canettieri G, Mastronuzzi A, Guardavaccaro D, Ayrault O, Infante P, Bufalieri F, Di Marcotullio L. Lospinoso Severini L, et al. Among authors: maroder m. Cell Death Differ. 2024 Feb;31(2):170-187. doi: 10.1038/s41418-023-01246-6. Epub 2023 Dec 7. Cell Death Differ. 2024. PMID: 38062245 Free PMC article.
Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation.
Coni S, Bordone R, Ivy DM, Yurtsever ZN, Di Magno L, D'Amico R, Cesaro B, Fatica A, Belardinilli F, Bufalieri F, Maroder M, De Smaele E, Di Marcotullio L, Giannini G, Agostinelli E, Canettieri G. Coni S, et al. Among authors: maroder m. Cancer Lett. 2023 Apr 10;559:216120. doi: 10.1016/j.canlet.2023.216120. Epub 2023 Mar 8. Cancer Lett. 2023. PMID: 36893894 Free article.
Islet Regeneration and Pancreatic Duct Glands in Human and Experimental Diabetes.
Overi D, Carpino G, Moretti M, Franchitto A, Nevi L, Onori P, De Smaele E, Federici L, Santorelli D, Maroder M, Reid LM, Cardinale V, Alvaro D, Gaudio E. Overi D, et al. Among authors: maroder m. Front Cell Dev Biol. 2022 Feb 4;10:814165. doi: 10.3389/fcell.2022.814165. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35186929 Free PMC article.
Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation.
Coni S, Serrao SM, Yurtsever ZN, Di Magno L, Bordone R, Bertani C, Licursi V, Ianniello Z, Infante P, Moretti M, Petroni M, Guerrieri F, Fatica A, Macone A, De Smaele E, Di Marcotullio L, Giannini G, Maroder M, Agostinelli E, Canettieri G. Coni S, et al. Among authors: maroder m. Cell Death Dis. 2020 Dec 10;11(12):1045. doi: 10.1038/s41419-020-03174-6. Cell Death Dis. 2020. PMID: 33303756 Free PMC article.
Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module.
Di Magno L, Manni S, Di Pastena F, Coni S, Macone A, Cairoli S, Sambucci M, Infante P, Moretti M, Petroni M, Nicoletti C, Capalbo C, De Smaele E, Di Marcotullio L, Giannini G, Battistini L, Goffredo BM, Iorio E, Agostinelli E, Maroder M, Canettieri G. Di Magno L, et al. Among authors: maroder m. Cell Rep. 2020 Feb 11;30(6):1735-1752.e7. doi: 10.1016/j.celrep.2020.01.024. Cell Rep. 2020. PMID: 32049007 Free article.
KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2.
Spiombi E, Angrisani A, Fonte S, De Feudis G, Fabretti F, Cucchi D, Izzo M, Infante P, Miele E, Po A, Di Magno L, Magliozzi R, Guardavaccaro D, Maroder M, Canettieri G, Giannini G, Ferretti E, Gulino A, Di Marcotullio L, Moretti M, De Smaele E. Spiombi E, et al. Among authors: maroder m. Oncogenesis. 2019 Nov 4;8(11):64. doi: 10.1038/s41389-019-0175-6. Oncogenesis. 2019. PMID: 31685809 Free PMC article.
A Smo/Gli Multitarget Hedgehog Pathway Inhibitor Impairs Tumor Growth.
Lospinoso Severini L, Quaglio D, Basili I, Ghirga F, Bufalieri F, Caimano M, Balducci S, Moretti M, Romeo I, Loricchio E, Maroder M, Botta B, Mori M, Infante P, Di Marcotullio L. Lospinoso Severini L, et al. Among authors: maroder m. Cancers (Basel). 2019 Oct 9;11(10):1518. doi: 10.3390/cancers11101518. Cancers (Basel). 2019. PMID: 31601026 Free PMC article.
Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation.
Antonucci L, Di Magno L, D'Amico D, Manni S, Serrao SM, Di Pastena F, Bordone R, Yurtsever ZN, Caimano M, Petroni M, Giorgi A, Schininà ME, Yates Iii JR, Di Marcotullio L, De Smaele E, Checquolo S, Capalbo C, Agostinelli E, Maroder M, Coni S, Canettieri G. Antonucci L, et al. Among authors: maroder m. Int J Oncol. 2019 Feb;54(2):505-514. doi: 10.3892/ijo.2018.4638. Epub 2018 Nov 19. Int J Oncol. 2019. PMID: 30483764 Free PMC article.
NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest.
Diluvio G, Del Gaudio F, Giuli MV, Franciosa G, Giuliani E, Palermo R, Besharat ZM, Pignataro MG, Vacca A, d'Amati G, Maroder M, Talora C, Capalbo C, Bellavia D, Checquolo S. Diluvio G, et al. Among authors: maroder m. Oncogenesis. 2018 May 25;7(5):42. doi: 10.1038/s41389-018-0051-9. Oncogenesis. 2018. PMID: 29795369 Free PMC article.
53 results