Al-Hashimi HM - Search Results

1

Rapid and accurate determination of atomistic RNA dynamic ensemble models using NMR and structure prediction.

Shi H, Rangadurai A, Abou Assi H, Roy R, Case DA, Herschlag D, Yesselman JD, Al-Hashimi HM. Shi H, et al. Nat Commun. 2020 Nov 2;11(1):5531. doi: 10.1038/s41467-020-19371-y. Nat Commun. 2020. PMID: 33139729 Free PMC article.

2

Towards structural genomics of RNA: rapid NMR resonance assignment and simultaneous RNA tertiary structure determination using residual dipolar couplings.

Al-Hashimi HM, Gorin A, Majumdar A, Gosser Y, Patel DJ. Al-Hashimi HM, et al. J Mol Biol. 2002 May 3;318(3):637-49. doi: 10.1016/S0022-2836(02)00160-2. J Mol Biol. 2002. PMID: 12054812

3

Visualizing spatially correlated dynamics that directs RNA conformational transitions.

Zhang Q, Stelzer AC, Fisher CK, Al-Hashimi HM. Zhang Q, et al. Nature. 2007 Dec 20;450(7173):1263-7. doi: 10.1038/nature06389. Nature. 2007. PMID: 18097416 Free article.

4

Extending the NMR spatial resolution limit for RNA by motional couplings.

Zhang Q, Al-Hashimi HM. Zhang Q, et al. Nat Methods. 2008 Mar;5(3):243-5. doi: 10.1038/nmeth.1180. Epub 2008 Feb 3. Nat Methods. 2008. PMID: 18246076

5

Constructing RNA dynamical ensembles by combining MD and motionally decoupled NMR RDCs: new insights into RNA dynamics and adaptive ligand recognition.

Frank AT, Stelzer AC, Al-Hashimi HM, Andricioaei I. Frank AT, et al. Nucleic Acids Res. 2009 Jun;37(11):3670-9. doi: 10.1093/nar/gkp156. Epub 2009 Apr 15. Nucleic Acids Res. 2009. PMID: 19369218 Free PMC article.

6

Direct evidence for methyl group coordination by carbon-oxygen hydrogen bonds in the lysine methyltransferase SET7/9.

Horowitz S, Yesselman JD, Al-Hashimi HM, Trievel RC. Horowitz S, et al. J Biol Chem. 2011 May 27;286(21):18658-63. doi: 10.1074/jbc.M111.232876. Epub 2011 Mar 18. J Biol Chem. 2011. PMID: 21454678 Free PMC article.

7

Characterizing RNA dynamics at atomic resolution using solution-state NMR spectroscopy.

Bothe JR, Nikolova EN, Eichhorn CD, Chugh J, Hansen AL, Al-Hashimi HM. Bothe JR, et al. Nat Methods. 2011 Oct 28;8(11):919-31. doi: 10.1038/nmeth.1735. Nat Methods. 2011. PMID: 22036746 Free PMC article. Review.

8

Visualizing transient low-populated structures of RNA.

Dethoff EA, Petzold K, Chugh J, Casiano-Negroni A, Al-Hashimi HM. Dethoff EA, et al. Nature. 2012 Nov 29;491(7426):724-8. doi: 10.1038/nature11498. Epub 2012 Oct 7. Nature. 2012. PMID: 23041928 Free PMC article.

9

Conservation and functional importance of carbon-oxygen hydrogen bonding in AdoMet-dependent methyltransferases.

Horowitz S, Dirk LM, Yesselman JD, Nimtz JS, Adhikari U, Mehl RA, Scheiner S, Houtz RL, Al-Hashimi HM, Trievel RC. Horowitz S, et al. J Am Chem Soc. 2013 Oct 16;135(41):15536-48. doi: 10.1021/ja407140k. Epub 2013 Oct 7. J Am Chem Soc. 2013. PMID: 24093804

10

Measuring similarity between dynamic ensembles of biomolecules.

Yang S, Salmon L, Al-Hashimi HM. Yang S, et al. Nat Methods. 2014 May;11(5):552-4. doi: 10.1038/nmeth.2921. Epub 2014 Apr 6. Nat Methods. 2014. PMID: 24705474 Free PMC article.

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