David SS - Search Results

1

Designer Fluorescent Adenines Enable Real-Time Monitoring of MUTYH Activity.

Zhu RY, Majumdar C, Khuu C, De Rosa M, Opresko PL, David SS, Kool ET. Zhu RY, et al. Among authors: david ss. ACS Cent Sci. 2020 Oct 28;6(10):1735-1742. doi: 10.1021/acscentsci.0c00369. Epub 2020 Aug 31. ACS Cent Sci. 2020. PMID: 33145410 Free PMC article.

2

Probing the requirements for recognition and catalysis in Fpg and MutY with nonpolar adenine isosteres.

Francis AW, Helquist SA, Kool ET, David SS. Francis AW, et al. Among authors: david ss. J Am Chem Soc. 2003 Dec 31;125(52):16235-42. doi: 10.1021/ja0374426. J Am Chem Soc. 2003. PMID: 14692765

3

Unnatural substrates reveal the importance of 8-oxoguanine for in vivo mismatch repair by MutY.

Livingston AL, O'Shea VL, Kim T, Kool ET, David SS. Livingston AL, et al. Among authors: david ss. Nat Chem Biol. 2008 Jan;4(1):51-8. doi: 10.1038/nchembio.2007.40. Epub 2007 Nov 18. Nat Chem Biol. 2008. PMID: 18026095 Free PMC article.

4

Surprising repair activities of nonpolar analogs of 8-oxoG expose features of recognition and catalysis by base excision repair glycosylases.

McKibbin PL, Kobori A, Taniguchi Y, Kool ET, David SS. McKibbin PL, et al. Among authors: david ss. J Am Chem Soc. 2012 Jan 25;134(3):1653-61. doi: 10.1021/ja208510m. Epub 2012 Jan 9. J Am Chem Soc. 2012. PMID: 22175854 Free PMC article.

5

Direct fluorescence monitoring of DNA base excision repair.

Ono T, Wang S, Koo CK, Engstrom L, David SS, Kool ET. Ono T, et al. Among authors: david ss. Angew Chem Int Ed Engl. 2012 Feb 13;51(7):1689-92. doi: 10.1002/anie.201108135. Epub 2012 Jan 12. Angew Chem Int Ed Engl. 2012. PMID: 22241823 Free PMC article. No abstract available.

6

Structure-Activity Relationships Reveal Key Features of 8-Oxoguanine: A Mismatch Detection by the MutY Glycosylase.

Manlove AH, McKibbin PL, Doyle EL, Majumdar C, Hamm ML, David SS. Manlove AH, et al. Among authors: david ss. ACS Chem Biol. 2017 Sep 15;12(9):2335-2344. doi: 10.1021/acschembio.7b00389. Epub 2017 Aug 8. ACS Chem Biol. 2017. PMID: 28723094 Free PMC article.

7

Fe-S Clusters and MutY Base Excision Repair Glycosylases: Purification, Kinetics, and DNA Affinity Measurements.

Nuñez NN, Majumdar C, Lay KT, David SS. Nuñez NN, et al. Among authors: david ss. Methods Enzymol. 2018;599:21-68. doi: 10.1016/bs.mie.2017.11.035. Epub 2018 Jan 10. Methods Enzymol. 2018. PMID: 29746241 Free PMC article.

8

Cellular Assays for Studying the Fe-S Cluster Containing Base Excision Repair Glycosylase MUTYH and Homologs.

Majumdar C, Nuñez NN, Raetz AG, Khuu C, David SS. Majumdar C, et al. Among authors: david ss. Methods Enzymol. 2018;599:69-99. doi: 10.1016/bs.mie.2017.12.006. Epub 2018 Jan 10. Methods Enzymol. 2018. PMID: 29746250 Free PMC article.

9

The Zinc Linchpin Motif in the DNA Repair Glycosylase MUTYH: Identifying the Zn²⁺ Ligands and Roles in Damage Recognition and Repair.

Nuñez NN, Khuu C, Babu CS, Bertolani SJ, Rajavel AN, Spear JE, Armas JA, Wright JD, Siegel JB, Lim C, David SS. Nuñez NN, et al. Among authors: david ss. J Am Chem Soc. 2018 Oct 17;140(41):13260-13271. doi: 10.1021/jacs.8b06923. Epub 2018 Oct 8. J Am Chem Soc. 2018. PMID: 30208271 Free PMC article.

10

Damage sensor role of UV-DDB during base excision repair.

Jang S, Kumar N, Beckwitt EC, Kong M, Fouquerel E, Rapić-Otrin V, Prasad R, Watkins SC, Khuu C, Majumdar C, David SS, Wilson SH, Bruchez MP, Opresko PL, Van Houten B. Jang S, et al. Among authors: david ss. Nat Struct Mol Biol. 2019 Aug;26(8):695-703. doi: 10.1038/s41594-019-0261-7. Epub 2019 Jul 22. Nat Struct Mol Biol. 2019. PMID: 31332353 Free PMC article.

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