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306 results

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A Challenging Task: Identifying Patients with Cancer of Unknown Primary (CUP) According to ESMO Guidelines: The CUPISCO Trial Experience.
Pauli C, Bochtler T, Mileshkin L, Baciarello G, Losa F, Ross JS, Pentheroudakis G, Zarkavelis G, Yalcin S, Özgüroğlu M, Beringer A, Scarato J, Mueller-Ohldach M, Thomas M, Moch H, Krämer A. Pauli C, et al. Among authors: mileshkin l. Oncologist. 2021 May;26(5):e769-e779. doi: 10.1002/onco.13744. Epub 2021 Mar 25. Oncologist. 2021. PMID: 33687747 Free PMC article. Clinical Trial.
Uncertainty and the unmet informational needs of patients with cancer of unknown primary (CUP): a cross-sectional multi-site study.
Guccione L, Fisher K, Mileshkin L, Tothill R, Bowtell D, Quinn S, DeFazio A, Karapetis CS, Wilcken N, Singh M, Steer C, Gao B, Warren M, Collins IM, Karanth N, Bryant C, Schofield P. Guccione L, et al. Among authors: mileshkin l. Support Care Cancer. 2022 Oct;30(10):8217-8229. doi: 10.1007/s00520-022-07228-7. Epub 2022 Jul 9. Support Care Cancer. 2022. PMID: 35804177 Free PMC article.
Immune and genomic biomarkers of immunotherapy response in cancer of unknown primary.
Posner A, Sivakumaran T, Pattison A, Etemadmoghadam D, Thio N, Wood C, Fisher K, Webb S, DeFazio A, Wilcken N, Gao B, Karapetis CS, Singh M, Collins IM, Richardson G, Steer C, Warren M, Karanth N, Fellowes A, Fox SB, Hicks RJ, Schofield P, Bowtell D, Prall OWJ, Tothill RW, Mileshkin L. Posner A, et al. Among authors: mileshkin l. J Immunother Cancer. 2023 Jan;11(1):e005809. doi: 10.1136/jitc-2022-005809. J Immunother Cancer. 2023. PMID: 36720497 Free PMC article.
Baseline mutational profiles of patients with carcinoma of unknown primary origin enrolled in the CUPISCO study.
Westphalen CB, Federer-Gsponer J, Pauli C, Karapetyan AR, Chalabi N, Durán-Pacheco G, Beringer A, Bochtler T, Cook N, Höglander E, Jin DX, Losa F, Mileshkin L, Moch H, Ross JS, Sokol ES, Tothill RW, Krämer A. Westphalen CB, et al. Among authors: mileshkin l. ESMO Open. 2023 Dec;8(6):102035. doi: 10.1016/j.esmoop.2023.102035. Epub 2023 Nov 2. ESMO Open. 2023. PMID: 37922692 Free PMC article.
Solving unknown primary cancer with earlier diagnosis - the SUPER-ED trial: study protocol for a stepped-wedge cluster randomised controlled trial to support earlier diagnosis for people presenting with malignancy of undefined primary origin.
Ugalde A, Tothill RW, Quinn S, Wong HL, Prall O, Mitchell C, Wickramasinghe N, Fedele C, Richards N, Todio E, Bryant C, Collins LG, McLean S, Ko HS, Akhurst T, Steer C, Gao B, Wong M, Georgiou C, Karanth N, Kuchel A, Nott L, Padinharakam S, Shackleton M, Collins IM, Singh M, Wong R, Wong ZW, Butler A, Sivakumaran T, Schofield P, Mileshkin L. Ugalde A, et al. Among authors: mileshkin l. BMC Cancer. 2025 Jan 29;25(1):171. doi: 10.1186/s12885-025-13506-4. BMC Cancer. 2025. PMID: 39881222 Free PMC article.
Whole genome sequencing improves tissue-of-origin diagnosis and treatment options for cancer of unknown primary.
Rebello RJ, Posner A, Dong R, Prall OWJ, Sivakumaran T, Mitchell CB, Flynn A, Caneborg A, Mitchell C, Kanwal S, Fedele C, Webb S, Fisher K, Wong HL, Balachander S, Zhu W, Nicolson S, Dimitriadis V, Wilcken N, DeFazio A, Gao B, Singh M, Collins IM, Steer C, Warren M, Karanth N, Xu H, Fellowes A, Hicks RJ, Stewart KP, Shale C, Priestley P, Dawson SJ, Vissers JHA, Fox SB, Schofield P, Bowtell D, Hofmann O, Grimmond SM, Mileshkin L, Tothill RW. Rebello RJ, et al. Among authors: mileshkin l. Nat Commun. 2025 May 20;16(1):4422. doi: 10.1038/s41467-025-59661-x. Nat Commun. 2025. PMID: 40393956 Free PMC article.
306 results