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Impact of trifluridine/tipiracil plus bevacizumab on tumor shrinkage and depth of response in refractory metastatic colorectal cancer: analysis of the SUNLIGHT trial.
Taieb J, Modest DP, Fakih M, Ciardiello F, Van Cutsem E, Elez E, Gravalos C, Bragagnoli AC, Barboux V, Roby L, Amellal N, Prager GW. Taieb J, et al. Among authors: modest dp. Eur J Cancer. 2025 Sep 9;227:115644. doi: 10.1016/j.ejca.2025.115644. Epub 2025 Jul 12. Eur J Cancer. 2025. PMID: 40694985 Free article. Clinical Trial.
Alternating gemcitabine plus nab-paclitaxel and gemcitabine alone versus continuous gemcitabine plus nab-paclitaxel after induction treatment of metastatic pancreatic cancer (ALPACA): a multicentre, randomised, open-label, phase 2 trial.
Dorman K, Boeck S, Caca K, Reichert M, Ettrich TJ, Oettle H, Waidmann O, Modest DP, Müller L, Michl P, Kanzler S, Pink D, Reinacher-Schick A, Geißler M, Pelz H, Kunzmann V, Held S, Schichtl T, Heinemann V, Kullmann F. Dorman K, et al. Among authors: modest dp. Lancet Gastroenterol Hepatol. 2024 Oct;9(10):935-943. doi: 10.1016/S2468-1253(24)00197-3. Epub 2024 Aug 16. Lancet Gastroenterol Hepatol. 2024. PMID: 39159648 Clinical Trial.
FOLFOXIRI Plus Cetuximab or Bevacizumab as First-Line Treatment of BRAFV600E-Mutant Metastatic Colorectal Cancer: The Randomized Phase II FIRE-4.5 (AIO KRK0116) Study.
Stintzing S, Heinrich K, Tougeron D, Modest DP, Schwaner I, Eucker J, Pihusch R, Stauch M, Kaiser F, Kahl C, Karthaus M, Müller C, Burkart C, Reinacher-Schick A, Kasper-Virchow S, Fischer von Weikersthal L, Krammer-Steiner B, Prager GW, Taieb J, Heinemann V. Stintzing S, et al. Among authors: modest dp. J Clin Oncol. 2023 Sep 1;41(25):4143-4153. doi: 10.1200/JCO.22.01420. Epub 2023 Jun 23. J Clin Oncol. 2023. PMID: 37352476 Clinical Trial.
Surgical treatment options following chemotherapy plus cetuximab or bevacizumab in metastatic colorectal cancer-central evaluation of FIRE-3.
Modest DP, Denecke T, Pratschke J, Ricard I, Lang H, Bemelmans M, Becker T, Rentsch M, Seehofer D, Bruns CJ, Gebauer B, Modest HI, Held S, Folprecht G, Heinemann V, Neumann UP. Modest DP, et al. Among authors: modest hi. Eur J Cancer. 2018 Jan;88:77-86. doi: 10.1016/j.ejca.2017.10.028. Epub 2017 Nov 28. Eur J Cancer. 2018. PMID: 29195117 Clinical Trial.
Factors That Influence Conversion to Resectability and Survival After Resection of Metastases in RAS WT Metastatic Colorectal Cancer (mCRC): Analysis of FIRE-3- AIOKRK0306.
Modest DP, Heinemann V, Folprecht G, Denecke T, Pratschke J, Lang H, Bemelmans M, Becker T, Rentsch M, Seehofer D, Bruns CJ, Gebauer B, Held S, Stahler A, Heinrich K, von Einem JC, Stintzing S, Neumann UP, Ricard I. Modest DP, et al. Ann Surg Oncol. 2020 Jul;27(7):2389-2401. doi: 10.1245/s10434-020-08219-w. Epub 2020 Mar 14. Ann Surg Oncol. 2020. PMID: 32172334 Free PMC article. Clinical Trial.
FIRE-9 - PORT / AIO-KRK-0418: a prospective, randomized, open, multicenter Phase III trial to investigate the efficacy of adjuvant/additive chemotherapy in patients with definitely-treated metastatic colorectal cancer.
Raschzok N, Stintzing S, Heinemann V, Rauch G, Ricke J, Guckenberger M, Kurreck A, Alig AHS, Stahler A, Bullinger L, Schmelzle M, Schöning W, Lurje G, Krenzien F, Haase O, Rau B, Gebauer B, Sauer IM, Pratschke J, Modest DP. Raschzok N, et al. Among authors: modest dp. BMC Cancer. 2022 Apr 2;22(1):359. doi: 10.1186/s12885-022-09422-6. BMC Cancer. 2022. PMID: 35366831 Free PMC article. Clinical Trial.
Viscoelastic properties of colorectal liver metastases reflect tumour cell viability.
Skrip LM, Moosburner S, Tang P, Guo J, Görner S, Tzschätzsch H, Brüggemann K, Walter KA, Hosse C, Fehrenbach U, Arnold A, Modest D, Krenzien F, Schöning W, Malinka T, Pratschke J, Papke B, Käs JA, Sack I, Sauer IM, Hillebrandt KH. Skrip LM, et al. J Transl Med. 2024 Aug 16;22(1):774. doi: 10.1186/s12967-024-05559-z. J Transl Med. 2024. PMID: 39152426 Free PMC article.
172 results