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Page 1
Cross-species analysis of enhancer logic using deep learning.
Minnoye L, Taskiran II, Mauduit D, Fazio M, Van Aerschot L, Hulselmans G, Christiaens V, Makhzami S, Seltenhammer M, Karras P, Primot A, Cadieu E, van Rooijen E, Marine JC, Egidy G, Ghanem GE, Zon L, Wouters J, Aerts S. Minnoye L, et al. Among authors: taskiran ii. Genome Res. 2020 Dec;30(12):1815-1834. doi: 10.1101/gr.260844.120. Epub 2020 Jul 30. Genome Res. 2020. PMID: 32732264 Free PMC article.
The transcription factor Grainy head primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes.
Jacobs J, Atkins M, Davie K, Imrichova H, Romanelli L, Christiaens V, Hulselmans G, Potier D, Wouters J, Taskiran II, Paciello G, González-Blas CB, Koldere D, Aibar S, Halder G, Aerts S. Jacobs J, et al. Among authors: taskiran ii. Nat Genet. 2018 Jul;50(7):1011-1020. doi: 10.1038/s41588-018-0140-x. Epub 2018 Jun 4. Nat Genet. 2018. PMID: 29867222 Free PMC article.
Identification of genomic enhancers through spatial integration of single-cell transcriptomics and epigenomics.
Bravo González-Blas C, Quan XJ, Duran-Romaña R, Taskiran II, Koldere D, Davie K, Christiaens V, Makhzami S, Hulselmans G, de Waegeneer M, Mauduit D, Poovathingal S, Aibar S, Aerts S. Bravo González-Blas C, et al. Among authors: taskiran ii. Mol Syst Biol. 2020 May;16(5):e9438. doi: 10.15252/msb.20209438. Mol Syst Biol. 2020. PMID: 32431014 Free PMC article.
Analysis of long and short enhancers in melanoma cell states.
Mauduit D, Taskiran II, Minnoye L, de Waegeneer M, Christiaens V, Hulselmans G, Demeulemeester J, Wouters J, Aerts S. Mauduit D, et al. Among authors: taskiran ii. Elife. 2021 Dec 7;10:e71735. doi: 10.7554/eLife.71735. Elife. 2021. PMID: 34874265 Free PMC article.
Decoding gene regulation in the fly brain.
Janssens J, Aibar S, Taskiran II, Ismail JN, Gomez AE, Aughey G, Spanier KI, De Rop FV, González-Blas CB, Dionne M, Grimes K, Quan XJ, Papasokrati D, Hulselmans G, Makhzami S, De Waegeneer M, Christiaens V, Southall T, Aerts S. Janssens J, et al. Among authors: taskiran ii. Nature. 2022 Jan;601(7894):630-636. doi: 10.1038/s41586-021-04262-z. Epub 2022 Jan 5. Nature. 2022. PMID: 34987221
Biallelic missense variants in ZBTB11 can cause intellectual disability in humans.
Fattahi Z, Sheikh TI, Musante L, Rasheed M, Taskiran II, Harripaul R, Hu H, Kazeminasab S, Alam MR, Hosseini M, Larti F, Ghaderi Z, Celik A, Ayub M, Ansar M, Haddadi M, Wienker TF, Ropers HH, Kahrizi K, Vincent JB, Najmabadi H. Fattahi Z, et al. Among authors: taskiran ii. Hum Mol Genet. 2018 Sep 15;27(18):3177-3188. doi: 10.1093/hmg/ddy220. Hum Mol Genet. 2018. PMID: 29893856
CNKSR1 gene defect can cause syndromic autosomal recessive intellectual disability.
Kazeminasab S, Taskiran II, Fattahi Z, Bazazzadegan N, Hosseini M, Rahimi M, Oladnabi M, Haddadi M, Celik A, Ropers HH, Najmabadi H, Kahrizi K. Kazeminasab S, et al. Among authors: taskiran ii. Am J Med Genet B Neuropsychiatr Genet. 2018 Dec;177(8):691-699. doi: 10.1002/ajmg.b.32648. Epub 2018 Nov 18. Am J Med Genet B Neuropsychiatr Genet. 2018. PMID: 30450701
The evolution of gene regulation in mammalian cerebellum development.
Sarropoulos I, Sepp M, Yamada T, Schäfer PSL, Trost N, Schmidt J, Schneider C, Drummer C, Mißbach S, Taskiran II, Hecker N, Bravo González-Blas C, Frömel R, Joshi P, Leushkin E, Arnskötter F, Leiss K, Okonechnikov K, Lisgo S, Palkovits M, Pääbo S, Cardoso-Moreira M, Kutscher LM, Behr R, Pfister SM, Aerts S, Kaessmann H. Sarropoulos I, et al. Among authors: taskiran ii. Science. 2026 Jan 29;391(6784):eadw9154. doi: 10.1126/science.adw9154. Epub 2026 Jan 29. Science. 2026. PMID: 41610256
Single-cell spatial multi-omics and deep learning dissect enhancer-driven gene regulatory networks in liver zonation.
Bravo González-Blas C, Matetovici I, Hillen H, Taskiran II, Vandepoel R, Christiaens V, Sansores-García L, Verboven E, Hulselmans G, Poovathingal S, Demeulemeester J, Psatha N, Mauduit D, Halder G, Aerts S. Bravo González-Blas C, et al. Among authors: taskiran ii. Nat Cell Biol. 2024 Jan;26(1):153-167. doi: 10.1038/s41556-023-01316-4. Epub 2024 Jan 5. Nat Cell Biol. 2024. PMID: 38182825 Free PMC article.
11 results