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Oligonucleotides for upregulating gene expression.
Khorkova O, Hsiao J, Wahlestedt C. Khorkova O, et al. Among authors: wahlestedt c. Pharm Pat Anal. 2013 Mar;2(2):215-29. doi: 10.4155/ppa.13.4. Pharm Pat Anal. 2013. PMID: 24237027 Review.
Regulation of the apolipoprotein gene cluster by a long noncoding RNA.
Halley P, Kadakkuzha BM, Faghihi MA, Magistri M, Zeier Z, Khorkova O, Coito C, Hsiao J, Lawrence M, Wahlestedt C. Halley P, et al. Among authors: wahlestedt c. Cell Rep. 2014 Jan 16;6(1):222-30. doi: 10.1016/j.celrep.2013.12.015. Epub 2014 Jan 2. Cell Rep. 2014. PMID: 24388749 Free PMC article.
Natural antisense transcripts.
Khorkova O, Myers AJ, Hsiao J, Wahlestedt C. Khorkova O, et al. Among authors: wahlestedt c. Hum Mol Genet. 2014 Sep 15;23(R1):R54-63. doi: 10.1093/hmg/ddu207. Epub 2014 May 16. Hum Mol Genet. 2014. PMID: 24838284 Free PMC article. Review.
Natural antisense transcripts as therapeutic targets.
Halley P, Khorkova O, Wahlestedt C. Halley P, et al. Among authors: wahlestedt c. Drug Discov Today Ther Strateg. 2013 Fall;10(3):e119-e125. doi: 10.1016/j.ddstr.2013.03.001. Drug Discov Today Ther Strateg. 2013. PMID: 25580147 Free PMC article. No abstract available.
Basic biology and therapeutic implications of lncRNA.
Khorkova O, Hsiao J, Wahlestedt C. Khorkova O, et al. Among authors: wahlestedt c. Adv Drug Deliv Rev. 2015 Jun 29;87:15-24. doi: 10.1016/j.addr.2015.05.012. Epub 2015 May 27. Adv Drug Deliv Rev. 2015. PMID: 26024979 Free PMC article. Review.
Upregulation of Haploinsufficient Gene Expression in the Brain by Targeting a Long Non-coding RNA Improves Seizure Phenotype in a Model of Dravet Syndrome.
Hsiao J, Yuan TY, Tsai MS, Lu CY, Lin YC, Lee ML, Lin SW, Chang FC, Liu Pimentel H, Olive C, Coito C, Shen G, Young M, Thorne T, Lawrence M, Magistri M, Faghihi MA, Khorkova O, Wahlestedt C. Hsiao J, et al. Among authors: wahlestedt c. EBioMedicine. 2016 Jul;9:257-277. doi: 10.1016/j.ebiom.2016.05.011. Epub 2016 May 13. EBioMedicine. 2016. PMID: 27333023 Free PMC article.
Developments in lncRNA drug discovery: where are we heading?
Blokhin I, Khorkova O, Hsiao J, Wahlestedt C. Blokhin I, et al. Among authors: wahlestedt c. Expert Opin Drug Discov. 2018 Sep;13(9):837-849. doi: 10.1080/17460441.2018.1501024. Epub 2018 Aug 6. Expert Opin Drug Discov. 2018. PMID: 30078338 Review.
320 results