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Suppression of ERK signalling promotes pluripotent epiblast in the human blastocyst.
Simon CS, McCarthy A, Woods L, Staneva D, Proks M, Salehin N, Lea G, Huang Q, Linneberg-Agerholm M, Faulkner A, Papathanasiou A, Elder K, Snell P, Christie L, Garcia P, Shaikly V, Taranissi M, Choudhary M, Herbert M, Hanna CW, Brickman JM, Niakan KK. Simon CS, et al. Nat Commun. 2025 Jul 28;16(1):6922. doi: 10.1038/s41467-025-61830-x. Nat Commun. 2025. PMID: 40721412 Free PMC article.
mTOR activity paces human blastocyst stage developmental progression.
Iyer DP, Khoei HH, van der Weijden VA, Kagawa H, Pradhan SJ, Novatchkova M, McCarthy A, Rayon T, Simon CS, Dunkel I, Wamaitha SE, Elder K, Snell P, Christie L, Schulz EG, Niakan KK, Rivron N, Bulut-Karslioğlu A. Iyer DP, et al. Among authors: simon cs. Cell. 2024 Nov 14;187(23):6566-6583.e22. doi: 10.1016/j.cell.2024.08.048. Epub 2024 Sep 26. Cell. 2024. PMID: 39332412 Free PMC article.
43 results