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Sulfatase-cleavable linkers for antibody-drug conjugates.
Bargh JD, Walsh SJ, Isidro-Llobet A, Omarjee S, Carroll JS, Spring DR. Bargh JD, et al. Among authors: spring dr. Chem Sci. 2020 Jan 27;11(9):2375-2380. doi: 10.1039/c9sc06410a. Chem Sci. 2020. PMID: 34084399 Free PMC article.
Synthesis of unprecedented scaffold diversity.
Galloway WR, Diáz-Gavilán M, Isidro-Llobet A, Spring DR. Galloway WR, et al. Among authors: spring dr. Angew Chem Int Ed Engl. 2009;48(7):1194-6. doi: 10.1002/anie.200805452. Angew Chem Int Ed Engl. 2009. PMID: 19137520
Diversity-oriented synthesis of macrocyclic peptidomimetics.
Isidro-Llobet A, Murillo T, Bello P, Cilibrizzi A, Hodgkinson JT, Galloway WR, Bender A, Welch M, Spring DR. Isidro-Llobet A, et al. Among authors: spring dr. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6793-8. doi: 10.1073/pnas.1015267108. Epub 2011 Mar 7. Proc Natl Acad Sci U S A. 2011. PMID: 21383137 Free PMC article.
Specific inhibition of CK2α from an anchor outside the active site.
Brear P, De Fusco C, Hadje Georgiou K, Francis-Newton NJ, Stubbs CJ, Sore HF, Venkitaraman AR, Abell C, Spring DR, Hyvönen M. Brear P, et al. Among authors: spring dr. Chem Sci. 2016 Nov 1;7(11):6839-6845. doi: 10.1039/c6sc02335e. Epub 2016 Jul 12. Chem Sci. 2016. PMID: 28451126 Free PMC article.
A new Pseudomonas quinolone signal (PQS) binding partner: MexG.
Hodgkinson JT, Gross J, Baker YR, Spring DR, Welch M. Hodgkinson JT, et al. Among authors: spring dr. Chem Sci. 2016 Apr 21;7(4):2553-2562. doi: 10.1039/c5sc04197j. Epub 2016 Jan 20. Chem Sci. 2016. PMID: 28660026 Free PMC article.
236 results