Klinger A - Search Results

1

A novel moniliformin derivative as pan-inhibitor of histone deacetylases triggering apoptosis of leukemia cells.

Lu X, Yan G, Dawood M, Klauck SM, Sugimoto Y, Klinger A, Fleischer E, Shan L, Efferth T. Lu X, et al. Among authors: klinger a. Biochem Pharmacol. 2021 Dec;194:114677. doi: 10.1016/j.bcp.2021.114677. Epub 2021 Jul 13. Biochem Pharmacol. 2021. PMID: 34265280

2

Inhibitors of the Candida albicans Major Facilitator Superfamily Transporter Mdr1p Responsible for Fluconazole Resistance.

Keniya MV, Fleischer E, Klinger A, Cannon RD, Monk BC. Keniya MV, et al. Among authors: klinger a. PLoS One. 2015 May 7;10(5):e0126350. doi: 10.1371/journal.pone.0126350. eCollection 2015. PLoS One. 2015. PMID: 25951180 Free PMC article.

3

Lawsone derivatives target the Wnt/β-catenin signaling pathway in multidrug-resistant acute lymphoblastic leukemia cells.

Hamdoun S, Fleischer E, Klinger A, Efferth T. Hamdoun S, et al. Among authors: klinger a. Biochem Pharmacol. 2017 Dec 15;146:63-73. doi: 10.1016/j.bcp.2017.10.008. Epub 2017 Oct 20. Biochem Pharmacol. 2017. PMID: 29061340

4

Identification of inhibitors of the polo-box domain of polo-like kinase 1 from natural and semisynthetic compounds.

Abdelfatah S, Fleischer E, Klinger A, Wong VKW, Efferth T. Abdelfatah S, et al. Among authors: klinger a. Invest New Drugs. 2020 Feb;38(1):1-9. doi: 10.1007/s10637-019-00752-0. Epub 2019 Mar 15. Invest New Drugs. 2020. PMID: 30877426

5

Novel 3,4-Dihydroisocoumarins Inhibit Human P-gp and BCRP in Multidrug Resistant Tumors and Demonstrate Substrate Inhibition of Yeast Pdr5.

Sachs J, Döhl K, Weber A, Bonus M, Ehlers F, Fleischer E, Klinger A, Gohlke H, Pietruszka J, Schmitt L, Teusch N. Sachs J, et al. Among authors: klinger a. Front Pharmacol. 2019 Apr 16;10:400. doi: 10.3389/fphar.2019.00400. eCollection 2019. Front Pharmacol. 2019. PMID: 31040786 Free PMC article.

6

Vitamin K₃ thio-derivative: a novel specific apoptotic inducer in the doxorubicin-sensitive and -resistant cancer cells.

Hegazy MF, Fukaya M, Dawood M, Yan G, Klinger A, Fleischer E, Zaglool AW, Efferth T. Hegazy MF, et al. Among authors: klinger a. Invest New Drugs. 2020 Jun;38(3):650-661. doi: 10.1007/s10637-019-00810-7. Epub 2019 Jun 29. Invest New Drugs. 2020. PMID: 31254176

7

MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate.

Abdelfatah S, Berg A, Huang Q, Yang LJ, Hamdoun S, Klinger A, Greten HJ, Fleischer E, Berg T, Wong VKW, Efferth T. Abdelfatah S, et al. Among authors: klinger a. Acta Pharm Sin B. 2019 Sep;9(5):1021-1034. doi: 10.1016/j.apsb.2019.02.001. Epub 2019 Feb 10. Acta Pharm Sin B. 2019. PMID: 31649851 Free PMC article.

8

Isopetasin and S-isopetasin as novel P-glycoprotein inhibitors against multidrug-resistant cancer cells.

Abdelfatah S, Böckers M, Asensio M, Kadioglu O, Klinger A, Fleischer E, Efferth T. Abdelfatah S, et al. Among authors: klinger a. Phytomedicine. 2021 Jun;86:153196. doi: 10.1016/j.phymed.2020.153196. Epub 2020 Mar 10. Phytomedicine. 2021. PMID: 32229058

9

Inhibition of cell migration and induction of apoptosis by a novel class II histone deacetylase inhibitor, MCC2344.

Dawood M, Fleischer E, Klinger A, Bringmann G, Shan L, Efferth T. Dawood M, et al. Among authors: klinger a. Pharmacol Res. 2020 Oct;160:105076. doi: 10.1016/j.phrs.2020.105076. Epub 2020 Jul 10. Pharmacol Res. 2020. PMID: 32659428

10

Putative molecular determinants mediating sensitivity or resistance towards carnosic acid tumor cell responses.

Mahmoud N, Saeed MEM, Sugimoto Y, Klinger A, Fleischer E, Efferth T. Mahmoud N, et al. Among authors: klinger a. Phytomedicine. 2020 Oct;77:153271. doi: 10.1016/j.phymed.2020.153271. Epub 2020 Jun 29. Phytomedicine. 2020. PMID: 32659679

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