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ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate Cancer.
Centenera MM, Scott JS, Machiels J, Nassar ZD, Miller DC, Zinonos I, Dehairs J, Burvenich IJG, Zadra G, Chetta PM, Bango C, Evergren E, Ryan NK, Gillis JL, Mah CY, Tieu T, Hanson AR, Carelli R, Bloch K, Panagopoulos V, Waelkens E, Derua R, Williams ED, Evdokiou A, Cifuentes-Rius A, Voelcker NH, Mills IG, Tilley WD, Scott AM, Loda M, Selth LA, Swinnen JV, Butler LM. Centenera MM, et al. Among authors: scott js, scott am. Cancer Res. 2021 Apr 1;81(7):1704-1718. doi: 10.1158/0008-5472.CAN-20-2511. Epub 2021 Feb 5. Cancer Res. 2021. PMID: 33547161
The application of mechanistic absorption, distribution, metabolism and excretion studies and physiologically-based pharmacokinetic modeling in the discovery of the next-generation oral selective estrogen receptor degrader camizestrant to achieve an acceptable human pharmacokinetic profile.
Gangl ET, Markandu R, Sharma P, Sykes A, Pop-Damkov P, Sarkar U, Andersson L, Morentin-Gutierrez P, Scott JS, Fretland AJ, Klinowska T, McGinnity DF. Gangl ET, et al. Among authors: scott js. Drug Metab Dispos. 2025 Aug;53(8):100110. doi: 10.1016/j.dmd.2025.100110. Epub 2025 Jun 19. Drug Metab Dispos. 2025. PMID: 40700858 Free article.
Correction: Emerging roles of cohesin-STAG2 in cancer.
Scott JS, Al Ayadi L, Epeslidou E, van Scheppingen RH, Mukha A, Kaaij LJT, Lutz C, Prekovic S. Scott JS, et al. Oncogene. 2025 Aug;44(29):2561-2562. doi: 10.1038/s41388-025-03479-w. Oncogene. 2025. PMID: 40542201 No abstract available.
Discovery and Validation of a Novel Class of Necroptosis Inhibitors Targeting RIPK1.
Soday L, Seripracharat C, Gray JL, Luz AFS, Howard RT, Singh R, Burden TJ, Bernardini E, Mateus-Pinheiro M, Petersen J, Gunnarsson A, Gunnarsson J, Aagaard A, Sjögren T, Maslen S, Bartlett EJ, Iles AF, Smith DM, Scott JS, Skehel M, Davis AM, Ressurreição AS, Moreira R, Rodrigues CMP, Shenoy AR, Tate EW. Soday L, et al. Among authors: scott js. ACS Chem Biol. 2025 Jul 18;20(7):1527-1543. doi: 10.1021/acschembio.5c00112. Epub 2025 Jun 20. ACS Chem Biol. 2025. PMID: 40539767 Free PMC article.
417 results