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The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors.
Nat Commun. 2022 Jul 4;13(1):3833. doi: 10.1038/s41467-022-31155-0.
Nat Commun. 2022.
PMID: 35781533
Free PMC article.
PLAG1 dampens protein synthesis to promote human hematopoietic stem cell self-renewal.
Keyvani Chahi A, Belew MS, Xu J, Chen HTT, Rentas S, Voisin V, Krivdova G, Lechman E, Marhon SA, De Carvalho DD, Dick JE, Bader GD, Hope KJ.
Keyvani Chahi A, et al. Among authors: chen htt.
Blood. 2022 Sep 1;140(9):992-1008. doi: 10.1182/blood.2021014698.
Blood. 2022.
PMID: 35639948
Free PMC article.
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Glutaredoxin 2 is essential for AML survival through mitochondrial permeability transition pore regulation.
Ling T, O'Brien C, St-Germain J, Rondeau V, Shi M, Berman JM, Cepa AK, Saez Raez P, Wunderlich M, Carter K, Stillwell C, Sexton CR, Culp-Hill R, Reisz JA, Adeel SA, Zeng AGX, Bansal S, Tsao E, Chen HTT, Dick JE, Minden MD, Arruda A, Amaya ML, Tikhonova AN, Hope K, D'Alessandro A, Raught B, Jones CL.
Ling T, et al. Among authors: chen htt.
Blood. 2025 Nov 14:blood.2025028933. doi: 10.1182/blood.2025028933. Online ahead of print.
Blood. 2025.
PMID: 41237364
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Allogeneic Stem Cell Transplantation: The Relevance of Conditioning Regime Intensity for Myelodysplastic Syndromes (MDS).
Berg T, Salter B, Radford M, Chen HTT, Leber B.
Berg T, et al. Among authors: chen htt.
Curr Oncol. 2025 May 30;32(6):319. doi: 10.3390/curroncol32060319.
Curr Oncol. 2025.
PMID: 40558262
Free PMC article.
Review.
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