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Page 1
PACA nanoparticles target and deliver sildenafil to rejuvenate aged mouse liver sinusoidal endothelial cells.
Voloshyna T, Holte C, Pospíšil J, Szafranska K, Fuskevåg OM, Strand SP, Åslund AKO, Mørch Y, Snipstad S, Sulheim E, Hunt NJ, Cogger VC, Couteur DGL, Dietrichs ES, McCourt PAG. Voloshyna T, et al. Among authors: cogger vc. Nanotheranostics. 2025 May 14;9(2):155-170. doi: 10.7150/ntno.103000. eCollection 2025. Nanotheranostics. 2025. PMID: 40568372 Free PMC article.
Liver specification of human iPSC-derived endothelial cells transplanted into mouse liver.
Yap KK, Schröder J, Gerrand YW, Dobric A, Kong AM, Fox AM, Knowles B, Banting SW, Elefanty AG, Stanley EG, Yeoh GC, Lockwood GP, Cogger VC, Morrison WA, Polo JM, Mitchell GM. Yap KK, et al. Among authors: cogger vc. JHEP Rep. 2024 Feb 1;6(5):101023. doi: 10.1016/j.jhepr.2024.101023. eCollection 2024 May. JHEP Rep. 2024. PMID: 38681862 Free PMC article.
Liver, ageing and disease.
Le Couteur DG, Ngu MC, Hunt NJ, Brandon AE, Simpson SJ, Cogger VC. Le Couteur DG, et al. Among authors: cogger vc. Nat Rev Gastroenterol Hepatol. 2025 Oct;22(10):680-695. doi: 10.1038/s41575-025-01099-z. Epub 2025 Jul 28. Nat Rev Gastroenterol Hepatol. 2025. PMID: 40721658 Review.
miR-27b-3p modulates liver sinusoidal endothelium dedifferentiation in chronic liver disease.
Abad-Jordà L, Martínez-Alcocer A, Guixé-Muntet S, Hunt NJ, Westwood LJ, Lozano JJ, Gallego-Durán R, Cogger VC, Fernández-Iglesias A, Gracia-Sancho J. Abad-Jordà L, et al. Among authors: cogger vc. Hepatol Commun. 2025 Apr 30;9(5):e0700. doi: 10.1097/HC9.0000000000000700. eCollection 2025 May 1. Hepatol Commun. 2025. PMID: 40304581 Free PMC article.
The ongoing challenge of slowing ageing through drug discovery.
Le Couteur DG, Simpson SJ, Cogger VC, Thillainadesan J, Anderson R, de Cabo R. Le Couteur DG, et al. Among authors: cogger vc. Expert Opin Drug Discov. 2025 Apr;20(4):401-404. doi: 10.1080/17460441.2025.2482063. Epub 2025 Mar 24. Expert Opin Drug Discov. 2025. PMID: 40099655 No abstract available.
Oral nanotherapeutic formulation of insulin with reduced episodes of hypoglycaemia.
Hunt NJ, Lockwood GP, Heffernan SJ, Daymond J, Ngu M, Narayanan RK, Westwood LJ, Mohanty B, Esser L, Williams CC, Kuncic Z, McCourt PAG, Le Couteur DG, Cogger VC. Hunt NJ, et al. Among authors: cogger vc. Nat Nanotechnol. 2024 Apr;19(4):534-544. doi: 10.1038/s41565-023-01565-2. Epub 2024 Jan 2. Nat Nanotechnol. 2024. PMID: 38168926 Free PMC article.
118 results