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Application of error-corrected sequencing technologies for in vivo regulatory mutagenicity assessment.
Yauk CL, Lynch AM, Dobrovolsky VN, Schuler M, Smith-Roe SL, Fitzgerald D, Higgins J, Honarvar N, Le Curieux F, Matsumura S, Minocherhomji S, Recio L, Salk JJ, Sugiyama KI, Suzuki T, Wills JW, Marchetti F. Yauk CL, et al. Among authors: smith roe sl. Regul Toxicol Pharmacol. 2026 Jan;164:105985. doi: 10.1016/j.yrtph.2025.105985. Epub 2025 Nov 8. Regul Toxicol Pharmacol. 2026. PMID: 41213378 Free PMC article. Review.
Development and Testing of a Novel Whole-body Exposure System for Investigative Studies of Radiofrequency Radiation in Rodents [Internet].
Wyde ME, Capstick MH, Hall SM, Hooth MJ, Kuster N, Ladbury JM, Roberts GK, Shipkowski KA, Shockley KR, Smith-Roe SL, Stout MD, Walker NJ. Wyde ME, et al. Among authors: smith roe sl. Research Triangle Park (NC): National Institute of Environmental Health Sciences; 2025 Aug. Research Triangle Park (NC): National Institute of Environmental Health Sciences; 2025 Aug. PMID: 40966368 Free Books & Documents. Review.
Transferability, Reproducibility and Sensitivity of Mutation Quantification by Duplex Sequencing.
Zhang S, Parsons BL, Fitzgerald D, Ashford A, Auman JT, Chen T, Dodge A, Elhajouji A, Pfaller L, Harris S, Higgins J, Hobbs CA, Marchetti F, Meier MJ, Myers MB, Salk J, Sahroui R, Schuster D, Settivari R, Smith-Roe SL, Yauk CL, Yan J, Williams A, Chen CL. Zhang S, et al. Among authors: smith roe sl. Environ Mol Mutagen. 2025 Aug;66(6-7):311-326. doi: 10.1002/em.70020. Epub 2025 Jun 30. Environ Mol Mutagen. 2025. PMID: 40586373 Free PMC article.
A proposed screening strategy for evaluating the genotoxicity potential of botanicals and botanical extracts.
Witt KL, van Benthem J, Kobets T, Chen G, Kelber O, Krzykwa J, MacGregor JT, Mei N, Mitchell CA, Rietjens I, Sarigol-Kilic Z, Smith-Roe SL, Stopper H, Thakkar Y, Zeiger E, Pfuhler S. Witt KL, et al. Among authors: smith roe sl. Food Chem Toxicol. 2025 Mar;197:115277. doi: 10.1016/j.fct.2025.115277. Epub 2025 Jan 23. Food Chem Toxicol. 2025. PMID: 39855614 Free article. Review.
Dose-Related Mutagenic and Clastogenic Effects of Benzo[b]fluoranthene in Mouse Somatic Tissues Detected by Duplex Sequencing and the Micronucleus Assay.
Schuster DM, LeBlanc DPM, Zhou G, Meier MJ, Dodge AE, White PA, Long AS, Williams A, Hobbs C, Diesing A, Smith-Roe SL, Salk JJ, Marchetti F, Yauk CL. Schuster DM, et al. Among authors: smith roe sl. Environ Sci Technol. 2024 Dec 10;58(49):21450-21463. doi: 10.1021/acs.est.4c07236. Epub 2024 Nov 27. Environ Sci Technol. 2024. PMID: 39602390 Free PMC article.
Dose-related Mutagenic and Clastogenic Effects of Benzo[b]fluoranthene in Mouse Somatic Tissues Detected by Duplex Sequencing and the Micronucleus Assay.
Schuster DM, LeBlanc DPM, Zhou G, Meier MJ, Dodge AE, White PA, Long AS, Williams A, Hobbs C, Diesing A, Smith-Roe SL, Salk JJ, Marchetti F, Yauk CL. Schuster DM, et al. Among authors: smith roe sl. bioRxiv [Preprint]. 2024 Jul 26:2024.07.26.605228. doi: 10.1101/2024.07.26.605228. bioRxiv. 2024. Update in: Environ Sci Technol. 2024 Dec 10;58(49):21450-21463. doi: 10.1021/acs.est.4c07236. PMID: 39211269 Free PMC article. Updated. Preprint.
Adopting duplex sequencing technology for genetic toxicity testing: A proof-of-concept mutagenesis experiment with N-ethyl-N-nitrosourea (ENU)-exposed rats.
Smith-Roe SL, Hobbs CA, Hull V, Todd Auman J, Recio L, Streicker MA, Rivas MV, Pratt GA, Lo FY, Higgins JE, Schmidt EK, Williams LN, Nachmanson D, Valentine Iii CC, Salk JJ, Witt KL. Smith-Roe SL, et al. Mutat Res Genet Toxicol Environ Mutagen. 2023 Oct;891:503669. doi: 10.1016/j.mrgentox.2023.503669. Epub 2023 Aug 3. Mutat Res Genet Toxicol Environ Mutagen. 2023. PMID: 37770135 Free PMC article.
Error-corrected next generation sequencing - Promises and challenges for genotoxicity and cancer risk assessment.
Marchetti F, Cardoso R, Chen CL, Douglas GR, Elloway J, Escobar PA, Harper T Jr, Heflich RH, Kidd D, Lynch AM, Myers MB, Parsons BL, Salk JJ, Settivari RS, Smith-Roe SL, Witt KL, Yauk CL, Young R, Zhang S, Minocherhomji S. Marchetti F, et al. Among authors: smith roe sl. Mutat Res Rev Mutat Res. 2023 Jul-Dec;792:108466. doi: 10.1016/j.mrrev.2023.108466. Epub 2023 Aug 27. Mutat Res Rev Mutat Res. 2023. PMID: 37643677 Free article. Review.
82 results