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The human proton pump inhibitors inhibit Mycobacterium tuberculosis rifampicin efflux and macrophage-induced rifampicin tolerance.
Lake MA, Adams KN, Nie F, Fowler E, Verma AK, Dei S, Teodori E, Sherman DR, Edelstein PH, Spring DR, Troll M, Ramakrishnan L. Lake MA, et al. Among authors: spring dr. Proc Natl Acad Sci U S A. 2023 Feb 14;120(7):e2215512120. doi: 10.1073/pnas.2215512120. Epub 2023 Feb 10. Proc Natl Acad Sci U S A. 2023. PMID: 36763530 Free PMC article.
Targeted covalent inhibitors of MDM2 using electrophile-bearing stapled peptides.
Charoenpattarapreeda J, Tan YS, Iegre J, Walsh SJ, Fowler E, Eapen RS, Wu Y, Sore HF, Verma CS, Itzhaki L, Spring DR. Charoenpattarapreeda J, et al. Among authors: spring dr. Chem Commun (Camb). 2019 Jul 14;55(55):7914-7917. doi: 10.1039/c9cc04022f. Epub 2019 Jun 21. Chem Commun (Camb). 2019. PMID: 31225847
Site-selective modification strategies in antibody-drug conjugates.
Walsh SJ , Bargh JD , Dannheim FM , Hanby AR , Seki H , Counsell AJ , Ou X , Fowler E , Ashman N , Takada Y , Isidro-Llobet A , Parker JS , Carroll JS , Spring DR . Walsh SJ , et al. Among authors: spring dr. Chem Soc Rev. 2021 Jan 21;50(2):1305-1353. doi: 10.1039/d0cs00310g. Epub 2020 Dec 8. Chem Soc Rev. 2021. PMID: 33290462 Review.
Diversity-oriented synthesis of macrocyclic peptidomimetics.
Isidro-Llobet A, Murillo T, Bello P, Cilibrizzi A, Hodgkinson JT, Galloway WR, Bender A, Welch M, Spring DR. Isidro-Llobet A, et al. Among authors: spring dr. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6793-8. doi: 10.1073/pnas.1015267108. Epub 2011 Mar 7. Proc Natl Acad Sci U S A. 2011. PMID: 21383137 Free PMC article.
Toolbox of Diverse Linkers for Navigating the Cellular Efficacy Landscape of Stapled Peptides.
Wu Y, Kaur A, Fowler E, Wiedmann MM, Young R, Galloway WRJD, Olsen L, Sore HF, Chattopadhyay A, Kwan TT, Xu W, Walsh SJ, de Andrade P, Janecek M, Arumugam S, Itzhaki LS, Lau YH, Spring DR. Wu Y, et al. Among authors: spring dr. ACS Chem Biol. 2019 Mar 15;14(3):526-533. doi: 10.1021/acschembio.9b00063. Epub 2019 Feb 7. ACS Chem Biol. 2019. PMID: 30702850
232 results